Question · asked by 1 review

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery: Adverse events

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events compared with stereotactic radiosurgery (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery
Adverse events · people with single or solitary brain metastasis
It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events compared with stereotactic radiosurgery (very low certainty).
Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis (2018) · Cochrane Headline outcomes only
RR 0.31 [0.07, 1.44]1 study · 64 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.