Question · asked by 1 review

CHLORPROMAZINE vs piperacetazine: Adverse effects/events: incidence of adverse effects ‐ as defined by each of the studies

Population
patients with schizophrenia
Intervention
CHLORPROMAZINE
Comparison
piperacetazine
Outcome
Adverse effects/events: incidence of adverse effects ‐ as defined by each of the studies

It is very uncertain whether chlorpromazine changes adverse effects/events: incidence of adverse effects ‐ as defined by… compared with piperacetazine (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Chlorpromazine vs piperacetazine
Adverse effects/events: incidence of adverse effects ‐ as defined by each of the studies · people with schizophrenia
It is very uncertain whether chlorpromazine changes adverse effects/events: incidence of adverse effects ‐ as defined by… compared with piperacetazine (very low certainty).
Chlorpromazine versus piperacetazine for schizophrenia (2018) · Cochrane Headline outcomes only
RR 1 [0.75, 1.33]3 studies · 74 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Chlorpromazine versus piperacetazine for schizophrenia
2018 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.