Question · asked by 1 review

Fluoride varnish vs placebo: Caries increment, surface index D(M)FS

Population
Children or adolescents
Intervention
Fluoride varnish
Comparison
placebo
Outcome
Caries increment, surface index D(M)FS

In the illustrative network meta-regression the SMD for caries increment showed a treatment-by-year interaction and differed between fluoride in varnish and placebo at randomization years 1954 to 1980; certainty was not graded.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Fluoride in varnish vs Placebo
Caries increment in permanent teeth (DMFS change from baseline) · Children or adolescents · At least 1 year or school year, Network meta-regression covariate: randomization year
In the illustrative network meta-regression the SMD for caries increment showed a treatment-by-year interaction and differed between fluoride in varnish and placebo at randomization years 1954 to 1980; certainty was not graded.
Graphs of study contributions and covariate distributions for network meta-regression. (2018) All outcomes
no estimate extractedNot reportedGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Graphs of study contributions and covariate distributions for network meta-regression.
2018 All outcomes
Not specifiedNot listedNot applicable

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.