Question · asked by 1 review

Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone: Adverse events

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone
Adverse events · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT) · 12 months
Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis (2018) · Cochrane All outcomes
See comment. Killeen 2016 reported no adverse events at follow-up examinations in either study arm. Tonetti 2012 reported that there were no serious adverse events.2 studies · 251 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis
2018 · Cochrane All outcomes
2017-05list not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.