Intranasal neostigmine vs placebo: Improved muscle function various methods1
It is very uncertain whether intranasal neostigmine changes improved muscle function various methods1 compared with placebo (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Intranasal neostigmine vs placebo Improved muscle function various methods1 · people with myasthenia gravis Acetylcholinesterase inhibitor treatment for myasthenia gravis (2014) · Cochrane Headline outcomes only | no estimate extracted | 10 participants | Very low |
Intranasal neostigmine vs placebo Improved muscle function various methods1 · people with myasthenia gravis It is very uncertain whether intranasal neostigmine changes improved muscle function various methods1 compared with placebo (very low certainty). Acetylcholinesterase inhibitor treatment for myasthenia gravis (2011) · Cochrane Headline outcomes onlyearlier version CD006986.PUB2, superseded | RR 19 [1.25, 287.92] | 1 study · 20 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Acetylcholinesterase inhibitor treatment for myasthenia gravis 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.