Question · asked by 1 review

Pregabalin vs placebo: Withdrawals due to adverse events

Population
children and adolescents with chronic non‐cancer pain
Intervention
Pregabalin
Comparison
placebo
Outcome
Withdrawals due to adverse events

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Pregabalin vs placebo
Withdrawals due to adverse events · children and adolescents (birth to 17 years of age) with chronic non‐cancer pain
Antiepileptic drugs for chronic non‐cancer pain in children and adolescents (2017) · Cochrane Headline outcomes only
no estimate extracted1 study · 107 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antiepileptic drugs for chronic non‐cancer pain in children and adolescents
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.