Question · asked by 1 review

Antioxidants vs placebo: Muscle soreness

Summary of findings: antioxidants showed no clear difference in muscle soreness compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Summary of findings: antioxidants vs placebo
Muscle soreness · mainly physically active individuals1 partaking in exercise2 designed to produce delayed onset muscle soreness
Summary of findings: antioxidants showed no clear difference in muscle soreness compared with placebo (low certainty).
Antioxidants for preventing and reducing muscle soreness after exercise (2017) · Cochrane Headline outcomes only
no estimate extracted21 studies · 525 participantsLow
Summary of findings: antioxidants vs placebo
Muscle soreness · mainly physically active individuals1 partaking in exercise2 designed to produce delayed onset muscle soreness
Summary of findings: antioxidants showed no clear difference in muscle soreness compared with placebo (moderate certainty).
Antioxidants for preventing and reducing muscle soreness after exercise (2017) · Cochrane Headline outcomes only
no estimate extracted41 studies · 936 participantsModerate
Summary of findings: antioxidants vs placebo
Muscle soreness · mainly physically active individuals1 partaking in exercise2 designed to produce delayed onset muscle soreness
Summary of findings: antioxidants showed no clear difference in muscle soreness compared with placebo (low certainty).
Antioxidants for preventing and reducing muscle soreness after exercise (2017) · Cochrane Headline outcomes only
no estimate extracted45 studies · 1047 participantsLow
Summary of findings: antioxidants vs placebo
Muscle soreness · mainly physically active individuals1 partaking in exercise2 designed to produce delayed onset muscle soreness
Summary of findings: antioxidants showed no clear difference in muscle soreness compared with placebo (moderate certainty).
Antioxidants for preventing and reducing muscle soreness after exercise (2017) · Cochrane Headline outcomes only
no estimate extracted28 studies · 657 participantsModerate
Summary of findings: antioxidants vs placebo
Muscle soreness · mainly physically active individuals1 partaking in exercise2 designed to produce delayed onset muscle soreness
Summary of findings: antioxidants showed no clear difference in muscle soreness compared with placebo (low certainty).
Antioxidants for preventing and reducing muscle soreness after exercise (2017) · Cochrane Headline outcomes only
no estimate extracted17 studies · 436 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antioxidants for preventing and reducing muscle soreness after exercise
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.