Celecoxib vs placebo: Exacerbation of ulcerative colitis
Celecoxib showed no clear difference in exacerbation of ulcerative colitis compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Celecoxib vs placebo Exacerbation of ulcerative colitis · patients with quiescent ulcerative colitis Celecoxib showed no clear difference in exacerbation of ulcerative colitis compared with placebo (low certainty). Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological… (2014) · Cochrane Headline outcomes only | RR 0.7 [0.23, 2.14] | 1 study · 222 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.