Question · asked by 1 review

Umeclidinium bromide vs placebo: Hospitalisations due to COPD exacerbations

Umeclidinium bromide showed no clear difference in number of participants with hospital admissions due to COPD… compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Umeclidinium bromide vs placebo
Number of participants with hospital admissions due to COPD exacerbation · people with chronic obstructive pulmonary disease (COPD)
Umeclidinium bromide showed no clear difference in number of participants with hospital admissions due to COPD… compared with placebo (low certainty).
Umeclidinium bromide versus placebo for people with chronic obstructive pulmonary disease (COPD) (2017) · Cochrane Headline outcomes only
OR 0.86 [0.25, 2.92]4 studies · 1922 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Umeclidinium bromide versus placebo for people with chronic obstructive pulmonary disease (COPD)
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.