Question · asked by 1 review

Preoperative antibiotics vs placebo or no antibiotic: Wound infection

Preoperative antibiotics probably leads to lower wound infections Proportion of wound infections compared with placebo or no antibiotic (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Preoperative antibiotics vs placebo or no antibiotic
Wound infections Proportion of wound infections · breast cancer surgery
Preoperative antibiotics probably leads to lower wound infections Proportion of wound infections compared with placebo or no antibiotic (moderate certainty).
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane Headline outcomes only
RR 0.67 [0.53, 0.85]10 studies · 2823 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.