Question · asked by 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone: Intraoperative pain or discomfort (dichotomous data)

Population
adults undergoing phacoemulsification cataract surgery
Intervention
Topical anaesthesia plus intracameral lidocaine
Comparison
topical anaesthesia alone
Outcome
Intraoperative pain or discomfort (dichotomous data)

Topical anaesthesia plus intracameral lidocaine probably leads to lower intraoperative pain or discomfort (dichotomous data) compared with topical anaesthesia alone (moderate certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%
FindingEffectStudiesGRADE certainty
Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone
Intraoperative pain or discomfort (dichotomous data) · adults undergoing phacoemulsification cataract surgery
Topical anaesthesia plus intracameral lidocaine probably leads to lower intraoperative pain or discomfort (dichotomous data) compared with topical anaesthesia alone (moderate certainty).
Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification… (2020) · Cochrane Headline outcomes onlyearlier version CD005276.PUB3, superseded
OR 0.4 [0.29, 0.57]Not reportedModerate
Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone
Intraoperative pain or discomfort (dichotomous data) · adults undergoing phacoemulsification cataract surgery
Topical anaesthesia plus intracameral lidocaine probably leads to lower intraoperative pain or discomfort (dichotomous data) compared with topical anaesthesia alone (moderate certainty).
Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification… (2020) · Cochrane Headline outcomes only
OR 0.4 [0.29, 0.57]Not reportedModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract surgery in adults
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.