Question · asked by 1 review

Sodium hypochlorite 1% with chlorhexidine 2% final rinse vs Sodium hypochlorite 1% with normal saline final rinse: Proportion of participants or samples with positive bacterial growth culture, up to 72 hours after the procedure

Population
Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical pathology, undergoing non-surgical root canal treatment
Intervention
Sodium hypochlorite 1% with chlorhexidine 2% final rinse
Comparison
Sodium hypochlorite 1% with normal saline final rinse
Outcome
Proportion of participants or samples with positive bacterial growth culture, up to 72 hours after the procedure

Sodium hypochlorite 1% with chlorhexidine 2% final rinse led to lower proportion of participants or samples with positive bacterial growth… compared with sodium hypochlorite 1% with normal saline final rinse; GRADE not reported.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Sodium hypochlorite 1% with chlorhexidine 2% final rinse vs Sodium hypochlorite 1% with normal saline final rinse
Proportion of participants or samples with positive bacterial growth culture, up to 72 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or…
Sodium hypochlorite 1% with chlorhexidine 2% final rinse led to lower proportion of participants or samples with positive bacterial growth… compared with sodium hypochlorite 1% with normal saline final rinse; GRADE not reported.
Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane All outcomes
RR 0.14 [0.02, 0.99]1 study · 24 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Irrigants for non‐surgical root canal treatment in mature permanent teeth
2012 · Cochrane All outcomes
2012-07Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.