Question · asked by 1 review
NSAIDs vs paracetamol: Adverse events
- Population
- Not specified
- Intervention
- NSAIDs
- Comparison
- paracetamol
- Outcome
- Adverse events
It is very uncertain whether NSAIDs changes adverse events compared with paracetamol (very low certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
NSAIDs vs paracetamol Adverse events It is very uncertain whether NSAIDs changes adverse events compared with paracetamol (very low certainty). Paracetamol (acetaminophen) or non‐steroidal anti‐inflammatory drugs, alone or combined, for pain relief in… (2023) · Cochrane Headline outcomes only | RR 1.71 [0.43, 6.9] | 3 studies · 281 participants | Very low |
NSAIDs vs paracetamol Adverse events It is very uncertain whether NSAIDs changes adverse events compared with paracetamol (very low certainty). Paracetamol (acetaminophen) or non‐steroidal anti‐inflammatory drugs, alone or combined, for pain relief in… (2016) · Cochrane Headline outcomes onlyearlier version CD011534.PUB2, superseded | RR 1.71 [0.43, 6.9] | 2 studies · 197 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Paracetamol (acetaminophen) or non‐steroidal anti‐inflammatory drugs, alone or combined, for pain relief in acute otitis media in children 2023 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- NSAIDs vs placebo · 1 review
- NSAIDs vs combined OCP · women with primary dysmenorrhoea · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.