Question · asked by 1 review
Pyridoxine vs control: Pre‐eclampsia
- Population
- pregnant women, either during the prenatal period or during labour.
- Intervention
- Pyridoxine
- Comparison
- control
- Outcome
- Pre‐eclampsia
Pyridoxine (B6) showed no clear difference in pre‐eclampsia ‐ Antenatal oral pyridoxine versus control compared with control (low certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Pyridoxine (B6) vs control Pre‐eclampsia ‐ Antenatal oral pyridoxine versus control · pregnant women, either during the prenatal period or during labour. Pyridoxine (B6) showed no clear difference in pre‐eclampsia ‐ Antenatal oral pyridoxine versus control compared with control (low certainty). Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes (2015) · Cochrane Headline outcomes only | RR 1.71 [0.85, 3.45] | 2 studies · 1197 participants | Low |
Pyridoxine (B6) vs control Pre‐eclampsia ‐ Antenatal pyridoxine lozenges versus control · pregnant women, either during the prenatal period or during labour. Pyridoxine (B6) showed no clear difference in pre‐eclampsia ‐ Antenatal pyridoxine lozenges versus control compared with control (low certainty). Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes (2015) · Cochrane Headline outcomes only | RR 1.43 [0.64, 3.22] | 1 study · 944 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes 2015 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.