Bisphosphonates vs placebo or no intervention: Adverse events
- Population
- patients with primary biliary cirrhosis.
- Intervention
- Bisphosphonates
- Comparison
- placebo or no intervention
- Outcome
- Adverse events
It is very uncertain whether bisphosphonates changes adverse events compared with placebo or no intervention (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Bisphosphonates vs placebo or no intervention Adverse events · patients with primary biliary cirrhosis. It is very uncertain whether bisphosphonates changes adverse events compared with placebo or no intervention (very low certainty). Bisphosphonates for osteoporosis in primary biliary cirrhosis (2011) · Cochrane Headline outcomes only | RR 1 [0.49, 2.04] | 2 studies · 46 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Bisphosphonates for osteoporosis in primary biliary cirrhosis 2011 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Bisphosphonates vs no bisphosphonates · adults with cystic fibrosis who have had a lung transplant · 1 review
- Bisphosphonates vs another bisphosphonate · patients with primary biliary cirrhosis. · 1 review
- Bisphosphonates vs placebo · children with cystic fibrosis who have not had a lung transplant · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.