Question · asked by 1 review
Desmopressin vs placebo: Major adverse events
- Population
- Not specified
- Intervention
- Desmopressin
- Comparison
- placebo
- Outcome
- Major adverse events
Desmopressin showed no clear difference in major adverse events compared with placebo (low certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Desmopressin vs placebo Major adverse events Desmopressin showed no clear difference in major adverse events compared with placebo (low certainty). Desmopressin for treating nocturia in men (2017) · Cochrane Headline outcomes only | RR 3.05 [0.13, 73.39] | 1 study · 115 participants | Low |
Desmopressin vs placebo Major adverse events It is very uncertain whether desmopressin changes major adverse events compared with placebo (very low certainty). Desmopressin for treating nocturia in men (2017) · Cochrane Headline outcomes only | RR 0.97 [0.1, 9.03] | 2 studies · 536 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Desmopressin for treating nocturia in men 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.