Bupropion vs placebo: Effect on later sexual function
Bupropion showed no clear difference in 50% reduction in score on the Arizona Sexual Experiences Scale… compared with placebo (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Bupropion vs placebo 50% reduction in score on the Arizona Sexual Experiences Scale (ASEX) (150 mg once daily dose) (The ASEX is a 5‐item self‐report inventory of sexual function) · people with antidepressant‐induced sexual dysfunction Bupropion showed no clear difference in 50% reduction in score on the Arizona Sexual Experiences Scale… compared with placebo (moderate certainty). Strategies for managing sexual dysfunction induced by antidepressant medication (2013) · Cochrane Headline outcomes only | RR 0.62 [0.09, 4.41] | 2 studies · 71 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Strategies for managing sexual dysfunction induced by antidepressant medication 2013 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.