Prophylactic levosimendan vs usual care: All‐cause mortality
Prophylactic levosimendan showed no clear difference in mortality compared with standard treatment (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Prophylactic levosimendan vs standard treatment Mortality · paediatric patients following heart surgery Prophylactic levosimendan showed no clear difference in mortality compared with standard treatment (low certainty). Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric… (2017) · Cochrane Headline outcomes onlyearlier version CD011312.PUB2, superseded | RR 0.47 [0.12, 1.82] | 3 studies · 123 participants | Low |
Prophylactic levosimendan vs standard treatment Mortality · paediatric patients following heart surgery Prophylactic levosimendan showed no clear difference in mortality compared with standard treatment (low certainty). Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric… (2017) · Cochrane Headline outcomes only | RR 0.47 [0.12, 1.82] | 3 studies · 123 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery for… 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.