Question · asked by 1 review

Plasma exchange vs sham exchange or supportive treatment: Dependency on a ventilator at 4 weeks

Plasma exchange probably leads to lower dependency on a ventilator at 4 weeks compared with sham exchange or supportive treatment (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Plasma exchange vs sham exchange or supportive treatment
Dependency on a ventilator at 4 weeks · people with Guillain‐Barré syndrome
Plasma exchange probably leads to lower dependency on a ventilator at 4 weeks compared with sham exchange or supportive treatment (moderate certainty).
Plasma exchange for Guillain‐Barré syndrome (2017) · Cochrane Headline outcomes only
RR 0.53 [0.39, 0.74]5 studies · 623 participantsModerate
Plasma exchange vs sham exchange or supportive treatment
On or not on a ventilator at 4 weeks · patients with Guillain‐Barré syndrome
Plasma exchange probably leads to lower on or not on a ventilator at 4 weeks compared with sham exchange or supportive treatment (moderate certainty).
Plasma exchange for Guillain‐Barré syndrome (2012) · Cochrane Headline outcomes onlyearlier version CD001798.PUB2, superseded
RR 0.53 [0.39, 0.74]5 studies · 623 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Plasma exchange for Guillain‐Barré syndrome
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.