Question · asked by 1 review

Tranexamic acid vs alternative haemostatic agents: Control of epistaxis: time to stop initial bleeding (proportion with bleeding controlled within 10 minutes)

Population
adults with nasal haemorrhage (epistaxis)
Intervention
Tranexamic acid
Comparison
alternative haemostatic agents
Outcome
Control of epistaxis: time to stop initial bleeding (proportion with bleeding controlled within 10 minutes)

Tranexamic acid probably leads to higher control of epistaxis: time to stop initial bleeding (proportion with… compared with other haemostatic agent (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Tranexamic acid vs other haemostatic agent
Control of epistaxis: time to stop initial bleeding (proportion with bleeding controlled within 10 minutes) · adults with nasal haemorrhage (epistaxis)
Tranexamic acid probably leads to higher control of epistaxis: time to stop initial bleeding (proportion with… compared with other haemostatic agent (moderate certainty).
Tranexamic acid for patients with nasal haemorrhage (epistaxis) (2018) · Cochrane Headline outcomes only
RR 2.35 [1.9, 2.92]3 studies · 460 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Tranexamic acid for patients with nasal haemorrhage (epistaxis)
2018 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.