PPI plus usual care vs usual care alone or chronic obstructive pulmonary disease: Exacerbations
PPI plus usual care may leads to lower exacerbation rate (participants with one or more) study duration: 12… compared with usual care alone or chronic obstructive pulmonary disease (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
PPI plus usual care vs usual care alone or chronic obstructive pulmonary disease Exacerbation rate (participants with one or more) study duration: 12 months · chronic obstructive pulmonary disease PPI plus usual care may leads to lower exacerbation rate (participants with one or more) study duration: 12… compared with usual care alone or chronic obstructive pulmonary disease (low certainty). Proton pump inhibitors for chronic obstructive pulmonary disease (2020) · Cochrane Headline outcomes only | RR 0.46 [0.26, 0.81] | 1 study · 100 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Proton pump inhibitors for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.