Question · asked by 1 review
CHLORPROMAZINE vs Clotiapine: Adverse effects: incidence of serious adverse effects. Movement disorders ‐ dyskinesia ‐short‐term
- Population
- patients with schizophrenia
- Intervention
- CHLORPROMAZINE
- Comparison
- Clotiapine
- Outcome
- Adverse effects: incidence of serious adverse effects. Movement disorders ‐ dyskinesia ‐short‐term
It is very uncertain whether chlorpromazine changes adverse effects: incidence of serious adverse effects. Movement… compared with clotiapine (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorpromazine vs Clotiapine Adverse effects: incidence of serious adverse effects. Movement disorders ‐ dyskinesia ‐short‐term · people with schizophrenia It is very uncertain whether chlorpromazine changes adverse effects: incidence of serious adverse effects. Movement… compared with clotiapine (very low certainty). Chlorpromazine versus clotiapine for schizophrenia (2017) · Cochrane Headline outcomes only | RR 3 [0.13, 71.15] | 1 study · 68 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Chlorpromazine versus clotiapine for schizophrenia 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.