Question · asked by 1 review

CHOLINERGIC DRUGS vs placebo: Secondary outcome: acceptability of treatment

Population
patients with antipsychotic‐induced tardive dyskinesia
Intervention
CHOLINERGIC DRUGS
Comparison
placebo
Outcome
Secondary outcome: acceptability of treatment

It is very uncertain whether CHOLINERGIC DRUGS changes acceptability of treatment: Leaving the study early compared with PLACEBO (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
CHOLINERGIC DRUGS vs PLACEBO
Acceptability of treatment: Leaving the study early · people with various psychiatric disorders (mainly schizophrenia) and antipsychotic‐induced tardive dyskinesia
It is very uncertain whether CHOLINERGIC DRUGS changes acceptability of treatment: Leaving the study early compared with PLACEBO (very low certainty).
Cholinergic medication for antipsychotic‐induced tardive dyskinesia (2018) · Cochrane Headline outcomes only
RR 1.09 [0.56, 2.1]12 studies · 288 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Cholinergic medication for antipsychotic‐induced tardive dyskinesia
2018 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.