Uric acid lowering therapies (UAR) vs placebo: Withdrawals due to adverse events
- Population
- hyperuricemia in hypertensive patients
- Intervention
- Uric acid lowering therapies (UAR)
- Comparison
- placebo
- Outcome
- Withdrawals due to adverse events
It is very uncertain whether uric acid (UA) lowering drug changes withdrawals due to adverse effects compared with placebo (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Uric acid (UA) lowering drug vs placebo Withdrawals due to adverse effects · hyperuricemia in hypertensive patients It is very uncertain whether uric acid (UA) lowering drug changes withdrawals due to adverse effects compared with placebo (very low certainty). Pharmacotherapy for hyperuricaemia in hypertensive patients (2017) · Cochrane Headline outcomes onlyearlier version CD008652.PUB3, superseded | RR 1.86 [0.43, 8.1] | 3 studies · 241 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacotherapy for hyperuricaemia in hypertensive patients 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Uric acid lowering therapies (UAR) vs placebo · hyperuricaemia in people with hypertension · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.