Question · asked by 1 review
Vaginal progesterone vs no treatment or placebo: Preterm birth
- Population
- Women with a multiple pregnancy
- Intervention
- Vaginal progesterone
- Comparison
- no treatment or placebo
- Outcome
- Preterm birth
Vaginal progesterone showed no clear difference in preterm birth less than 37 weeks compared with no treatment or placebo (moderate certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Vaginal progesterone vs no treatment or placebo Preterm birth less than 37 weeks · Women with a multiple pregnancy Vaginal progesterone showed no clear difference in preterm birth less than 37 weeks compared with no treatment or placebo (moderate certainty). Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple… (2019) · Cochrane Headline outcomes only | RR 0.97 [0.89, 1.06] | 6 studies · 1597 participants | Moderate |
Vaginal progesterone vs no treatment or placebo Preterm birth less than 37 weeks · Women with a multiple pregnancy Vaginal progesterone showed no clear difference in preterm birth less than 37 weeks compared with no treatment or placebo (moderate certainty). Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple… (2017) · Cochrane Headline outcomes onlyearlier version CD012024.PUB2, superseded | RR 0.97 [0.89, 1.06] | 6 studies · 1597 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple pregnancy 2019 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.