Question · asked by 1 review
Sodium hypochlorite 5.25% with hydrogen peroxide 3% vs Normal saline: Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure
- Population
- Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or periapical pathology, undergoing non-surgical root canal treatment
- Intervention
- Sodium hypochlorite 5.25% with hydrogen peroxide 3%
- Comparison
- Normal saline
- Outcome
- Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure
Sodium hypochlorite 5.25% with hydrogen peroxide 3% showed no clear difference in proportion of participants with moderate to severe pain 72 hours to… compared with normal saline; GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Sodium hypochlorite 5.25% with hydrogen peroxide 3% vs Normal saline Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Sodium hypochlorite 5.25% with hydrogen peroxide 3% showed no clear difference in proportion of participants with moderate to severe pain 72 hours to… compared with normal saline; GRADE not reported. Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane All outcomes | RR 0.65 [0.2, 2.0] | 1 study · 161 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Irrigants for non‐surgical root canal treatment in mature permanent teeth 2012 · Cochrane All outcomes | 2012-07 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.