Same question across reviews · CL0035

aetiology :: Exposure/condition: systemic-oral -> Caries (unspecified)

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
3
Questions
20
current versions
GRADE rated
0
Review overlap (CCA)
0.000
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
HIV-infected children on antiretroviral therapy (HI) vs HIV-exposed but uninfected children (HEU)
Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Prospective follow-up, Cohort studies
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
OR 2.88 [1.71, 4.84]NRUngraded
HIV-infected children on antiretroviral therapy (HI) vs HIV-exposed but uninfected children (HEU)
Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
OR 3.73 [1.88, 7.40]NRUngraded
HAART (highly active antiretroviral therapy, >=3 drugs) vs HIV-positive not receiving HAART (standard ART or HAART-naive)
Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies; DMFT index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
OR 1.29 [0.59, 2.84]NRUngraded
HAART (highly active antiretroviral therapy, >=3 drugs) vs HIV-positive not receiving HAART (standard ART or HAART-naive)
Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies; deft index
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
OR 1.09 [0.65, 1.82]NRUngraded
HIV-infected children on antiretroviral therapy (HI) vs HIV-unexposed uninfected children (HUU)
Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (case-control), Case-control studies
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
OR 1.61 [1.02, 2.56]NRUngraded
HIV-infected children on antiretroviral therapy (HI) vs HIV-unexposed uninfected children (HUU)
Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies
Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025)
OR 1.80 [0.98, 3.28]NRUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Non-standard periodontitis definition
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.38 [1.07, 1.79]2 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Adjusted OR
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.28 [0.85, 1.93]2 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Standard periodontitis definition
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.62 [1.20, 2.18]8 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Age 30-64 years
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.67 [1.37, 2.03]3 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Crude OR
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.69 [1.41, 2.01]8 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Female
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.36 [0.74, 2.49]2 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Overall
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.57 [1.20, 2.07]10 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Male
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.48 [1.26, 1.74]2 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Severe periodontitis
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 2.14 [1.74, 2.64]7 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Age 65 to over 75 years
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.69 [1.44, 1.98]2 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Moderate periodontitis
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.38 [1.15, 1.66]7 studiesUngraded
Periodontitis vs No periodontitis (periodontal health or gingivitis)
Dental caries (prevalence) · Adults · Mild periodontitis
Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024)
OR 1.65 [0.45, 6.05]1 studyUngraded
GERD vs Healthy controls
Dental caries · Adults
Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020)
no estimate extracted3 studiesUngraded
GERD vs Healthy individuals without reflux (controls)
Dental caries (Decayed Missing Filled index) · Adults with gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR)
Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020)
Three studies reported higher decayed-missing-filled index scores or a positive association between GERD and caries compared with controls (Yoshikawa, Song, Watanabe); no pooled estimate.3 studiesUngraded

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