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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
20 questions in 3 reviews · cluster CL0035
current versionsNo studies 0 · 0%Ungraded 20 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
HIV-infected children on antiretroviral therapy (HI) vs HIV-exposed but uninfected children (HEU) Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Prospective follow-up, Cohort studies Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025) | OR 2.88 [1.71, 4.84] | NR | Ungraded |
HIV-infected children on antiretroviral therapy (HI) vs HIV-exposed but uninfected children (HEU) Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025) | OR 3.73 [1.88, 7.40] | NR | Ungraded |
HAART (highly active antiretroviral therapy, >=3 drugs) vs HIV-positive not receiving HAART (standard ART or HAART-naive) Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies; DMFT index Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025) | OR 1.29 [0.59, 2.84] | NR | Ungraded |
HAART (highly active antiretroviral therapy, >=3 drugs) vs HIV-positive not receiving HAART (standard ART or HAART-naive) Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies; deft index Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025) | OR 1.09 [0.65, 1.82] | NR | Ungraded |
HIV-infected children on antiretroviral therapy (HI) vs HIV-unexposed uninfected children (HUU) Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (case-control), Case-control studies Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025) | OR 1.61 [1.02, 2.56] | NR | Ungraded |
HIV-infected children on antiretroviral therapy (HI) vs HIV-unexposed uninfected children (HUU) Dental caries (presence/absence) · Children and adolescents under 18 years with HIV · Not specified (cross-sectional), Cross-sectional studies Association between antiretroviral therapy and dental caries in children and adolescents with HIV: a… (2025) | OR 1.80 [0.98, 3.28] | NR | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Non-standard periodontitis definition Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.38 [1.07, 1.79] | 2 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Adjusted OR Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.28 [0.85, 1.93] | 2 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Standard periodontitis definition Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.62 [1.20, 2.18] | 8 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Age 30-64 years Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.67 [1.37, 2.03] | 3 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Crude OR Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.69 [1.41, 2.01] | 8 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Female Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.36 [0.74, 2.49] | 2 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Overall Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.57 [1.20, 2.07] | 10 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Male Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.48 [1.26, 1.74] | 2 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Severe periodontitis Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 2.14 [1.74, 2.64] | 7 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Age 65 to over 75 years Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.69 [1.44, 1.98] | 2 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Moderate periodontitis Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.38 [1.15, 1.66] | 7 studies | Ungraded |
Periodontitis vs No periodontitis (periodontal health or gingivitis) Dental caries (prevalence) · Adults · Mild periodontitis Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | OR 1.65 [0.45, 6.05] | 1 study | Ungraded |
GERD vs Healthy controls Dental caries · Adults Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020) | no estimate extracted | 3 studies | Ungraded |
GERD vs Healthy individuals without reflux (controls) Dental caries (Decayed Missing Filled index) · Adults with gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR) Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020) | Three studies reported higher decayed-missing-filled index scores or a positive association between GERD and caries compared with controls (Yoshikawa, Song, Watanabe); no pooled estimate. | 3 studies | Ungraded |