Same question across reviews · CL0016
aetiology :: Exposure: microbial -> Caries (unspecified)
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
16
current versions
GRADE rated
0
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Time period: before 2017 RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 4.89 [2.79, 8.58] | 10 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample collection: dental plaque RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 4.08 [2.65, 6.27] | 13 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Region: Europe RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 10.13 [6.01, 17.09] | 5 studies · 635 participants | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study quality (NOS): good RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 5.32 [2.89, 9.80] | 7 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample collection: saliva RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 4.70 [2.44, 9.09] | 7 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Overall (all 22 studies, random-effects) RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 4.42 [3.14, 6.24] | 22 studies · 3301 participants | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample size: >=100 (Table 6; abstract text erroneously states '>=1000') RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 4.65 [2.57, 8.42] | 6 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample collection: oral swab RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 9.55 [2.17, 42.01] | 2 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study design: case-control RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 5.30 [1.72, 16.31] | 2 studies · 708 participants | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Region: Asia RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 3.62 [2.53, 5.20] | 12 studies · 2347 participants | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample size: <100 (Table 6; abstract text erroneously states '<1000') RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 4.35 [2.75, 6.89] | 16 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Time period: 2018 and later RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 4.17 [2.62, 6.64] | 12 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study design: cross-sectional RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 4.30 [2.92, 6.33] | 20 studies · 2593 participants | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study quality (NOS): moderate RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 3.84 [2.24, 6.57] | 11 studies | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Region: America/Canada/Brazil/Chile RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 3.98 [1.14, 13.87] | 5 studies · 319 participants | Ungraded |
Presence of oral Candida albicans vs Absence of oral Candida albicans Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study quality (NOS): low RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024) | OR 5.14 [2.12, 12.48] | 4 studies | Ungraded |