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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

16 questions in 1 reviews · cluster CL0016

current versions
No studies 0 · 0%Ungraded 16 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Intervention categories, outcome domains and clusters are a proposed key pending human validation. Clear all filters

QuestionEffectEvidenceStatus / GRADE
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Time period: before 2017
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 4.89 [2.79, 8.58]10 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample collection: dental plaque
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 4.08 [2.65, 6.27]13 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Region: Europe
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 10.13 [6.01, 17.09]5 studies · 635 participantsUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study quality (NOS): good
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 5.32 [2.89, 9.80]7 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample collection: saliva
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 4.70 [2.44, 9.09]7 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Overall (all 22 studies, random-effects)
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 4.42 [3.14, 6.24]22 studies · 3301 participantsUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample size: >=100 (Table 6; abstract text erroneously states '>=1000')
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 4.65 [2.57, 8.42]6 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample collection: oral swab
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 9.55 [2.17, 42.01]2 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study design: case-control
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 5.30 [1.72, 16.31]2 studies · 708 participantsUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Region: Asia
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 3.62 [2.53, 5.20]12 studies · 2347 participantsUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample size: <100 (Table 6; abstract text erroneously states '<1000')
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 4.35 [2.75, 6.89]16 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Time period: 2018 and later
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 4.17 [2.62, 6.64]12 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study design: cross-sectional
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 4.30 [2.92, 6.33]20 studies · 2593 participantsUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study quality (NOS): moderate
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 3.84 [2.24, 6.57]11 studiesUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Region: America/Canada/Brazil/Chile
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 3.98 [1.14, 13.87]5 studies · 319 participantsUngraded
Presence of oral Candida albicans vs Absence of oral Candida albicans
Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Study quality (NOS): low
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A… (2024)
OR 5.14 [2.12, 12.48]4 studiesUngraded