Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Scaffold-Based Biomaterials for Periodontal Regeneration in Periodontitis: A Systematic Review and Meta-Analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Expression of Vascular Endothelial Growth Factor Using Platelet Rich Fibrin (PRF) and Nanohydroxyapatite (nano-HA) in Treatment of Periodontal… Bahammam 2021 · Bahammam Maha A, Attia Mai S · Saudi journal of biological sciences PMID:33424378 | 2021 | 4 | 1 | not extracted yet |
| Adjunctive effect of collagen membrane coverage to L-PRF in the treatment of periodontal intrabony defects: a randomized controlled clinical trial… Mubarak 2023 · Mubarak Ramy, Adel-Khattab Doaa, et al. · BMC oral health PMID:37667213 | 2023 | 3 | none stated | not extracted yet |
| Treatment of periodontal intrabony defects using bovine porous bone mineral and guided tissue regeneration with/without platelet-rich fibrin: A… Liu 2021 · Liu Kaining, Huang Zhen, et al. · Journal of periodontology PMID:33569807 | 2021 | 3 | none stated | not extracted yet |
| Evaluation of nanofiber scaffolds laden Ashvakatri in the management of chronic periodontitis-a randomized, controlled split pocket study. Dubey et al., 2025 · Dubey Pragati, Mittal Neelam, et al. · Journal of oral biology and craniofacial research PMID:40895264 | 2025 | 2 | none stated | not extracted yet |
| The use of integrin binding domain loaded hydrogel (RGD) with minimally invasive surgical technique in treatment of periodontal intrabony defect: a… Abd El-Azeem 2023 · Abd El-Azeem Shaimaa Hamdy, Khalil Ahmed Abdallah, et al. · Journal of applied oral science : revista FOB PMID:38126565 | 2023 | 2 | none stated | not extracted yet |
| Efficacy of periodontal minimally invasive surgery with and without regenerative materials for treatment of intrabony defect: a randomized clinical… Liu 2022 · Liu Bei, Ouyang Xiangying, et al. · Clinical oral investigations PMID:34414521 | 2022 | 2 | none stated | not extracted yet |
| Guided tissue regeneration of intrabony defects with perforated barrier membranes, simvastatin, and EDTA root surface modification: A clinical and… Issa 2020 · Issa Dalia Rasheed, Abdel-Ghaffar Khaled A, et al. · Journal of periodontal research PMID:31448832 | 2020 | 2 | none stated | not extracted yet |
| Comparison of GTR, T-PRF and open-flap debridement in the treatment of intrabony defects with endo-perio lesions: a randomized controlled trial. Ustaoglu 2020 · Ustaoğlu G, Uğur Aydin Z, et al. · Medicina oral, patologia oral y cirugia bucal PMID:31880284 | 2020 | 2 | none stated | not extracted yet |
| Treatment of intrabony defects with modified perforated membranes in aggressive periodontitis: a 12-month randomized controlled trial. Gorski 2018 · Górski Bartłomiej, Jalowski Stanisław, et al. · Clinical oral investigations PMID:29411112 | 2018 | 2 | none stated | not extracted yet |
| Native vs. ribosome-crosslinked collagen membranes for periodontal regeneration: A randomized clinical trial. Wang 2025b · Wang Yiwei, Xia Yiru, et al. · Journal of periodontal research PMID:38962931 | 2025 | 1 | none stated | not extracted yet |
| Crosslinked Versus Non-Crosslinked Resorbable Collagen Membranes for Periodontal Regeneration: A Multicenter, Randomized, Double-Blind,… Wang 2025a · Wang Yiwei, Yan Fuhua, et al. · Journal of periodontal research PMID:39799466 | 2025 | 1 | none stated | not extracted yet |
| Low-Speed Platelet-Rich Fibrin Membrane in Conjunction With Demineralized Freeze-Dried Bone Allograft (DFDBA) Compared to Collagen Membrane With… Almoliky 2025 · Almoliky Najeeb, Hosny Manal, et al. · International journal of dentistry PMID:40028653 | 2025 | 1 | none stated | not extracted yet |
| Clinical and radiographic evaluation of melatonin and chitosan loaded nanoparticles in the treatment of periodontal intra-bony defects: A Randomized… Al-agooz 2025 · Al-Agooz Amira, Ata Fatma, et al. · Clinical oral investigations PMID:40312586 | 2025 | 1 | none stated | not extracted yet |
| A Randomized Controlled Study on the Treatment of Isolated Interdental Intrabony Defects Using the Modified Minimally Invasive Surgical Technique… Sun 2025 · Sun Yuzhe, Zhang Haidong, et al. · Journal of clinical periodontology PMID:40386833 | 2025 | 1 | none stated | not extracted yet |
| A comparative study of platelet-rich fibrin plugs versus biphasic calcium phosphate in treating infrabony defects in patients with periodontitis:… Arumugam 2025 · Arumugam Parkavi, Baburaj Mala Dixit, et al. · Journal of clinical and experimental dentistry PMID:40485961 | 2025 | 1 | none stated | not extracted yet |
| Early healing after regenerative periodontal surgery with or without antibiotics. Dolińska 2025 · Dolińska Ewa, Pietruska Małgorzata, et al. · Dental and medical problems PMID:40843516 | 2025 | 1 | none stated | not extracted yet |
| Clinical evaluation of injectable platelet-rich fibrin with synthetic nanocrystalline hydroxyapatite bone graft for the treatment of intrabony… Rithesh 2025 · Rithesh K, Gopinath Sharika, et al. · Journal of Indian Society of Periodontology PMID:40951743 | 2025 | 1 | none stated | not extracted yet |
| Treatment of Unfavorable Intrabony Defects with Autogenous Bone Graft in Combination with Leukocyte- and Platelet-Rich Fibrin or Collagen Membranes:… Balice 2024 · Balice Giuseppe, Paolantonio Michele, et al. · Medicina (Kaunas, Lithuania) PMID:39064520 | 2024 | 1 | none stated | not extracted yet |
| Regenerative Surgery of Mandibular Class II Furcation Defects: A Comparison of Two Techniques in a Randomized Clinical Trial with 3D CBCT… Limiroli 2023 · Limiroli Enrico, Acerboni Alessia, et al. · The International journal of periodontics & restorative dentistry PMID:36661872 | 2023 | 1 | none stated | not extracted yet |
| Clinical And Radiographic Assessment Of Autogenous Dentin Nanoparticles In Treatment Of Stage Iii Periodontitis: A Split-Mouth Clinical Study. Elgendy 2023 · Elgendy Enas Ahmed, Elgendy Ahmed Mohamed, et al. · JPMA. The Journal of the Pakistan Medical Association PMID:37482878 | 2023 | 1 | none stated | not extracted yet |
| Evaluation of Osteogenic Potential of Fucoidan Containing Chitosan Hydrogel in the Treatment of Periodontal Intra-Bony Defects-A Randomized Clinical… Eshwar 2023 · Eshwar Shruthi, Konuganti Kranti, et al. · Gels (Basel, Switzerland) PMID:37504452 | 2023 | 1 | none stated | not extracted yet |
| Evaluation of PRF and PLA-PGA Membrane Along with Hydroxyapatite Crystal Collagen Fibers Bone Graft in the Treatment of Infrabony Defects. Deepika 2023 · Deepika Masurkar, G Jaiswal Priyanka, et al. · The journal of contemporary dental practice PMID:37622620 | 2023 | 1 | none stated | not extracted yet |
| Clinical and Radiographic Evaluation of Calcium Phosphate-Poly(lactide-co-glycolide) Graft in Regeneration of Intrabony Defects: Randomized Control… Ojha 2024 · Ojha Moitri, Rao Deepika Pawar Chandrashekara, et al. · The journal of contemporary dental practice PMID:38317387 | 2023 | 1 | none stated | not extracted yet |
| Regenerative potential of biphasic calcium phosphate and enamel matrix derivatives in the treatment of isolated interproximal intrabony defects: a… Pal 2022 · Pal Pritish Chandra, Bali Ashish, et al. · Journal of Yeungnam medical science PMID:36050839 | 2022 | 1 | none stated | not extracted yet |
| Comparative evaluation of the efficacy of amniotic membrane with collagen membrane along with demineralized freeze-dried bone allograft in the… Agrawal 2022 · Agrawal Eiti, Chopra Rahul, et al. · Journal of Indian Society of Periodontology PMID:36339389 | 2022 | 1 | none stated | not extracted yet |
| Efficacy of inorganic bovine bone combined with leukocyte and platelet-rich fibrin or collagen membranes for treating unfavorable periodontal… Rexhepi 2021 · Rexhepi Imena, Paolantonio Michele, et al. · Journal of periodontology PMID:33547808 | 2021 | 1 | none stated | not extracted yet |
| Clinical efficacy of amniotic membrane with biphasic calcium phosphate in guided tissue regeneration of intrabony defects- a randomized controlled… Venkatesan 2021 · Venkatesan Nivedha, Lavu Vamsi, et al. · Biomaterials research PMID:33958006 | 2021 | 1 | none stated | not extracted yet |
| Extracellular matrix containing nanocomposite bone graft in periodontal regeneration - A randomized controlled clinical and radiographic evaluation. Deshpande 2021 · Deshpande Abhinav Prakash, Baburaj Mala Dixit, et al. · Journal of Indian Society of Periodontology PMID:34393402 | 2021 | 1 | none stated | not extracted yet |
| Comparative Evaluation of Efficacy between Recombinant Human Bone Morphogenetic Protein-2 Impregnated with Absorbable Sponge and Platelet-Rich… Sneha 2021 · Sneha Kidambi, Sowjanya Kacharla, et al. · Contemporary clinical dentistry PMID:35068843 | 2021 | 1 | none stated | not extracted yet |
| Development of biodegradable silkworm cocoon derived silk membrane for GTR in the treatment of grade II furcation Sankar 2020 · Archana R Sankar, Sheela Kumar Gujjari, et al. · International Journal of Research in Pharmaceutical Sciences DOI:10.26452/ijrps.v11i2.2033 | 2020 | 1 | none stated | not extracted yet |
| Adjunctive use of enamel matrix derivatives to porcine-derived xenograft for the treatment of one-wall intrabony defects: Two-year longitudinal… Lee 2020 · Lee Jae-Hong, Kim Do-Hyung, et al. · Journal of periodontology PMID:31811645 | 2020 | 1 | none stated | not extracted yet |
| Sankar 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |