Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Therapeutic efficacy of mesenchymal stem cells in periodontal regeneration: a systematic review and meta-analysis of clinical trials.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Human intrabony defect regeneration with micrografts containing dental pulp stem cells: A randomized controlled clinical trial. Ferrarotti 2018 · Ferrarotti Francesco, Romano Federica, et al. · Journal of clinical periodontology PMID:29779220 | 2018 | 5 | none stated | not extracted yet |
| Periodontal regeneration using a xenogeneic bone substitute seeded with autologous periodontal ligament-derived mesenchymal stem cells: A 12-month… Sanchez 2020 · Sánchez Nerea, Fierravanti Ludovica, et al. · Journal of clinical periodontology PMID:32946590 | 2020 | 4 | none stated | not extracted yet |
| Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial. Chen 2016 · Chen Fa-Ming, Gao Li-Na, et al. · Stem cell research & therapy PMID:26895633 | 2016 | 4 | none stated | not extracted yet |
| A tissue-engineered biocomplex for periodontal reconstruction. A proof-of-principle randomized clinical study. Apatzidou 2021 · Apatzidou Danae A, Bakopoulou Athina A, et al. · Journal of clinical periodontology PMID:33899259 | 2021 | 3 | none stated | not extracted yet |
| Impact of allogeneic dental pulp stem cell injection on tissue regeneration in periodontitis: a multicenter randomized clinical trial. Liu 2025 · Liu Yi, Liu Yitong, et al. · Signal transduction and targeted therapy PMID:40739139 | 2025 | 2 | none stated | not extracted yet |
| Platelet Rich Fibrin Matrix (PRFM) and Peripheral Blood Mesenchymal Stem Cells (PBMSCs) in the management of intraosseous defects - A randomized… Sreeparvathy 2024 · SREEPARVATHY R, BELLUDI Sphoorthi Anup, et al. · Journal of Applied Oral Science DOI:10.1590/1678-7757-2023-0442 | 2024 | 2 | none stated | not extracted yet |
| Platelet Rich Fibrin Matrix (PRFM) and Peripheral Blood Mesenchymal Stem Cells (PBMSCs) in the management of intraosseous defects - A randomized… Sreeparvathy 2024 · Sreeparvathy R, Belludi Sphoorthi Anup, et al. · Journal of applied oral science : revista FOB PMID:39109750 | 2024 | 2 | none stated | not extracted yet |
| A tissue‐engineered biocomplex for periodontal reconstruction. A proof‐of‐principle randomized clinical study Apatzidou 2021 · Apatzidou Danae A., Bakopoulou Athina A., et al. · Journal of Clinical Periodontology DOI:10.1111/jcpe.13474 | 2021 | 2 | none stated | not extracted yet |
| Regenerative potential of cultured gingival fibroblasts in treatment of periodontal intrabony defects (randomized clinical and biochemical trial). Abdal-Wahab 2020 · Abdal-Wahab Mahetab, Abdel Ghaffar Khaled A, et al. · Journal of periodontal research PMID:32080858 | 2020 | 2 | 1 | not extracted yet |
| Human intrabony defect regeneration with micrografts containing dental pulp stem cells: A randomized controlled clinical trial Ferrarotti 2018 · Ferrarotti Francesco, Romano Federica, et al. · Journal of Clinical Periodontology DOI:10.1111/jcpe.12931 | 2018 | 2 | none stated | not extracted yet |
| Efficacy and safety of autologous adipose-derived stem cells combined with platelet-rich plasma for periodontal regeneration: a multicenter,… Tobita 2026 · Tobita Morikuni, Masubuchi Yosuke, et al. · Regenerative Therapy DOI:10.1016/j.reth.2026.101062 | 2026 | 1 | none stated | not extracted yet |
| Efficacy and safety of autologous adipose-derived stem cells combined with platelet-rich plasma for periodontal regeneration: a multicenter,… Tobita 2026 · Tobita Morikuni, Masubuchi Yosuke, et al. · Regenerative therapy PMID:41624073 | 2026 | 1 | none stated | not extracted yet |
| Impact of allogeneic dental pulp stem cell injection on tissue regeneration in periodontitis: a multicenter randomized clinical trial Liu 2025 · Liu Yi, Liu Yitong, et al. · Signal Transduction and Targeted Therapy DOI:10.1038/s41392-025-02320-w | 2025 | 1 | none stated | not extracted yet |
| Evaluation of autologous periodontal stem cells niche in the treatment of periodontal intrabony defects: A split-mouth randomized controlled trial. Chanreiphy 2025 · Chanreiphy Hungyo, Gupta Vineeta, et al. · Journal of Indian Society of Periodontology PMID:40636765 | 2025 | 1 | none stated | not extracted yet |
| Periodontal regeneration using a xenogeneic bone substitute seeded with autologous periodontal ligament‐derived mesenchymal stem cells: A 12‐month… Sanchez 2020 · Sánchez Nerea, Fierravanti Ludovica, et al. · Journal of Clinical Periodontology DOI:10.1111/jcpe.13368 | 2020 | 1 | none stated | not extracted yet |
| Regenerative potential of cultured gingival fibroblasts in treatment of periodontal intrabony defects (randomized clinical and biochemical trial) Abdal-Wahab 2020 · Abdal‐Wahab Mahetab, Abdel Ghaffar Khaled A., et al. · Journal of Periodontal Research DOI:10.1111/jre.12728 | 2020 | 1 | none stated | not extracted yet |
| Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial Chen 2016 · Chen Fa-Ming, Gao Li-Na, et al. · Stem Cell Research & Therapy DOI:10.1186/s13287-016-0288-1 | 2016 | 1 | none stated | not extracted yet |
| Stem Cells Cultured on Beta Tricalcium Phosphate (β-TCP) in Combination with Recombinant Human Platelet-Derived Growth Factor - BB (rh-PDGF-BB) for… Dhote 2015 · Dhote Roshani, Charde Priti, et al. · Journal of stem cells PMID:27144828 | 2015 | 1 | none stated | not extracted yet |