Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Diagnostic Accuracy and Clinical Utility of Salivary Biomarkers in Oral Squamous Cell Carcinoma: A Meta-Analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| A novel saliva-based miRNA profile to diagnose and predict oral cancer Balakittnen 2024 · Balakittnen Jaikrishna, Ekanayake Weeramange Chameera, et al. · International Journal of Oral Science DOI:10.1038/s41368-023-00273-w | 2024 | 3 | none stated | not extracted yet |
| A novel saliva-based miRNA profile to diagnose and predict oral cancer. Balakittnen 2024 · Balakittnen Jaikrishna, Ekanayake Weeramange Chameera, et al. · International journal of oral science PMID:38368395 | 2024 | 3 | none stated | not extracted yet |
| Evaluation of Diagnostic Significance of Salivary miRNA-184 and miRNA-21 in Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders. Garg 2023 · Garg Aarushi, Urs Aadithya B, et al. · Head and neck pathology PMID:38015343 | 2023 | 3 | none stated | not extracted yet |
| "Salivary LINC00657 and miRNA-106a as diagnostic biomarkers for oral squamous cell carcinoma, an observational diagnostic study". Tarrad 2023 · Tarrad Nayroz Abdel Fattah, Hassan Sandy, et al. · BMC oral health PMID:38087258 | 2023 | 3 | none stated | not extracted yet |
| Genome-wide study of salivary miRNAs identifies miR-423-5p as promising diagnostic and prognostic biomarker in oral squamous cell carcinoma. Romani 2021 · Romani Chiara, Salviato Elisa, et al. · Theranostics PMID:33456584 | 2021 | 3 | none stated | not extracted yet |
| Serum and salivary levels of chemerin and MMP-9 in oral squamous cell carcinoma and oral premalignant lesions. Ghallab 2017 · Ghallab Noha A, Shaker Olfat G · Clinical oral investigations PMID:27161218 | 2017 | 3 | none stated | not extracted yet |
| Evaluation of Diagnostic Significance of Salivary miRNA-184 and miRNA-21 in Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders Garg 2023 · Garg Aarushi, Urs Aadithya B., et al. · Head and Neck Pathology DOI:10.1007/s12105-023-01600-7 | 2023 | 2 | none stated | not extracted yet |
| “Salivary LINC00657 and miRNA-106a as diagnostic biomarkers for oral squamous cell carcinoma, an observational diagnostic study” Tarrad 2023 · Tarrad Nayroz Abdel Fattah, Hassan Sandy, et al. · BMC Oral Health DOI:10.1186/s12903-023-03726-0 | 2023 | 2 | none stated | not extracted yet |
| Salivary miR-31-5p, miR-345-3p, and miR-424-3p Are Reliable Biomarkers in Patients with Oral Squamous Cell Carcinoma. Scholtz 2022 · Scholtz Beáta, Horváth József, et al. · Pathogens (Basel, Switzerland) PMID:35215172 | 2022 | 2 | none stated | not extracted yet |
| A novel panel of clinically relevant miRNAs signature accurately differentiates oral cancer from normal mucosa. Mehterov 2022 · Mehterov Nikolay, Sacconi Andrea, et al. · Frontiers in oncology PMID:36531016 | 2022 | 2 | none stated | not extracted yet |
| Salivary exosomal miR-24-3p serves as a potential detective biomarker for oral squamous cell carcinoma screening. He 2020 · He Lihong, Ping Fan, et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie PMID:31704611 | 2020 | 2 | none stated | not extracted yet |
| Evaluation of saliva and plasma cytokine biomarkers in patients with oral squamous cell carcinoma. Lee 2018 · Lee L T, Wong Y K, et al. · International journal of oral and maxillofacial surgery PMID:29174861 | 2018 | 2 | none stated | not extracted yet |
| Salivary miRNA panel to detect HPV-positive and HPV-negative head and neck cancer patients. Wan 2017 · Wan Yunxia, Vagenas Dimitrios, et al. · Oncotarget PMID:29245955 | 2017 | 2 | none stated | not extracted yet |
| Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: a pilot study. Duz 2016 · Duz Mehmet Bugrahan, Karatas Omer Faruk, et al. · Cellular oncology (Dordrecht, Netherlands) PMID:26650483 | 2016 | 2 | none stated | not extracted yet |
| Evaluation of salivary and serum Exosomal mRNAs as biomarkers for the diagnosis and prognosis of oral squamous cell carcinoma Kumar 2025 · Kumar Sarwareddy Kartik, Kanaparthi Neeharika, et al. · Scientific Reports DOI:10.1038/s41598-025-22246-1 | 2025 | 1 | none stated | not extracted yet |
| Evaluation of salivary and serum Exosomal mRNAs as biomarkers for the diagnosis and prognosis of oral squamous cell carcinoma. Kumar 2025 · Kumar Sarwareddy Kartik, Kanaparthi Neeharika, et al. · Scientific reports PMID:41184439 | 2025 | 1 | none stated | not extracted yet |
| Clinical validation of a saliva-based matrix metalloproteinase-1 rapid strip test for detection of oral cavity cancer Chu 2024 · Chu Lichieh Julie, Chang Ya-Ting, et al. · Biomedical Journal DOI:10.1016/j.bj.2023.04.002 | 2024 | 1 | none stated | not extracted yet |
| Clinical validation of a saliva-based matrix metalloproteinase-1 rapid strip test for detection of oral cavity cancer. Chu 2024 · Chu Lichieh Julie, Chang Ya-Ting, et al. · Biomedical journal PMID:37044249 | 2024 | 1 | none stated | not extracted yet |
| Integrity and quantity of salivary cell‐free <scp>DNA</scp> as a potential molecular biomarker in oral cancer: A preliminary study Rapado-Gonzalez 2022 · Rapado‐González Óscar, López‐Cedrún José Luis, et al. · Journal of Oral Pathology & Medicine DOI:10.1111/jop.13299 | 2022 | 1 | none stated | not extracted yet |
| A novel panel of clinically relevant miRNAs signature accurately differentiates oral cancer from normal mucosa Mehterov 2022 · Mehterov Nikolay, Sacconi Andrea, et al. · Frontiers in Oncology DOI:10.3389/fonc.2022.1072579 | 2022 | 1 | none stated | not extracted yet |
| Integrity and quantity of salivary cell-free DNA as a potential molecular biomarker in oral cancer: A preliminary study. Rapado-Gonzalez 2022 · Rapado-González Óscar, López-Cedrún José Luis, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:35416334 | 2022 | 1 | none stated | not extracted yet |
| Identification of potential salivary biomarker panels for oral squamous cell carcinoma Anu 2021 · Jain Anu, Kotimoole Chinmaya Narayana, et al. · Scientific Reports DOI:10.1038/s41598-021-82635-0 | 2021 | 1 | none stated | not extracted yet |
| Identification of potential salivary biomarker panels for oral squamous cell carcinoma. Anu 2021 · Jain Anu, Kotimoole Chinmaya Narayana, et al. · Scientific reports PMID:33564003 | 2021 | 1 | none stated | not extracted yet |
| Salivary exosomal miR-24-3p serves as a potential detective biomarker for oral squamous cell carcinoma screening He 2020 · He Lihong, Ping Fan, et al. · Biomedicine & Pharmacotherapy DOI:10.1016/j.biopha.2019.109553 | 2020 | 1 | none stated | not extracted yet |
| Evaluation of saliva and plasma cytokine biomarkers in patients with oral squamous cell carcinoma Lee 2018 · Lee L.T., Wong Y.K., et al. · International Journal of Oral and Maxillofacial Surgery DOI:10.1016/j.ijom.2017.09.016 | 2018 | 1 | none stated | not extracted yet |
| Salivary Circular RNAs Hsa_Circ_0001874 and Hsa_Circ_0001971 as Novel Biomarkers for the Diagnosis of Oral Squamous Cell Carcinoma Zhao 2018 · Zhao Si-Yu, Wang Jun, et al. · Cellular Physiology and Biochemistry DOI:10.1159/000491624 | 2018 | 1 | none stated | not extracted yet |
| Salivary extracellular vesicle-associated miRNAs as potential biomarkers in oral squamous cell carcinoma Gai 2018 · Gai Chiara, Camussi Francesco, et al. · BMC Cancer DOI:10.1186/s12885-018-4364-z | 2018 | 1 | none stated | not extracted yet |
| Salivary extracellular vesicle-associated miRNAs as potential biomarkers in oral squamous cell carcinoma. Gai 2018 · Gai Chiara, Camussi Francesco, et al. · BMC cancer PMID:29669525 | 2018 | 1 | none stated | not extracted yet |
| Salivary Circular RNAs Hsa_Circ_0001874 and Hsa_Circ_0001971 as Novel Biomarkers for the Diagnosis of Oral Squamous Cell Carcinoma. Zhao 2018 · Zhao Si-Yu, Wang Jun, et al. · Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology PMID:29991057 | 2018 | 1 | none stated | not extracted yet |
| Salivary miRNA panel to detect HPV-positive and HPV-negative head and neck cancer patients Wan 2017 · Wan Yunxia, Vagenas Dimitrios, et al. · Oncotarget DOI:10.18632/oncotarget.21725 | 2017 | 1 | none stated | not extracted yet |
| Role of salivary biomarkers in early detection of oral squamous cell carcinoma Awasthi 2017 · Awasthi Nidhi · Indian Journal of Pathology and Microbiology DOI:10.4103/ijpm.ijpm_140_16 | 2017 | 1 | none stated | not extracted yet |
| Role of salivary biomarkers in early detection of oral squamous cell carcinoma. Awasthi 2017 · Awasthi Nidhi · Indian journal of pathology & microbiology PMID:29323056 | 2017 | 1 | none stated | not extracted yet |
| Serum and salivary levels of chemerin and MMP-9 in oral squamous cell carcinoma and oral premalignant lesions Ghallab 2016 · Ghallab Noha A., Shaker Olfat G. · Clinical Oral Investigations DOI:10.1007/s00784-016-1846-8 | 2016 | 1 | none stated | not extracted yet |
| Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: a pilot study Duz 2016 · Duz Mehmet Bugrahan, Karatas Omer Faruk, et al. · Cellular Oncology DOI:10.1007/s13402-015-0259-z | 2015 | 1 | none stated | not extracted yet |