Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Effects of photobiomodulation on oral mucositis, oral pain, xerostomia, salivary flow rate, and quality of life in patients with head and…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Photobiomodulation for the prevention of oral side effects secondary to head and neck cancer therapy: results of a randomised, single-blind clinical… Vianna Camolesi 2025 · Vianna Camolesi Gisela Cristina, Prado-Pena Irene Beatriz, et al. · Oral oncology PMID:40184883 | 2025 | 2 | 1 | not extracted yet |
| Evaluation of the Effect of Photobiomodulation on Radiation-Induced Xerostomia in Head and Neck Cancer Patients: A Randomized Clinical Trial. Mosannen Mozaffari 2024 · Mosannen Mozaffari Pegah, Delavarian Zahra, et al. · Journal of lasers in medical sciences PMID:38655042 | 2024 | 2 | none stated | not extracted yet |
| Photobiomodulation for the management of xerostomia and oral mucositis in patients with cancer: a randomized clinical trial. de Carvalho 2023 · de Carvalho E Silva Roberta Mariano, Mendes Fausto Medeiros, et al. · Lasers in medical science PMID:37060370 | 2023 | 2 | none stated | not extracted yet |
| Effect of photobiomodulation on salivary flow and composition, xerostomia and quality of life of patients during head and neck radiotherapy in short… Louzeiro 2020 · Louzeiro Gabriel Campos, Cherubini Karen, et al. · Journal of photochemistry and photobiology. B, Biology PMID:32570059 | 2020 | 2 | none stated | not extracted yet |
| Effect of low level laser therapy in the reduction of oral complications in patients with cancer of the head and neck submitted to radiotherapy. Oton-Leite 2013 · Oton-Leite Angélica Ferreira, Elias Larissa Santana Arantes, et al. · Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry PMID:24164228 | 2013 | 2 | none stated | not extracted yet |
| Mohamed 2022 matched by author and year (probable) | NR | 2 | 1 | not extracted yet |
| Effectiveness of Photobiomodulation (low-level laser therapy) on treatment of oral mucositis (OM) induced by chemoradiotherapy in head and neck… Barati 2025 · Barati Shadi, Motevasseli Safa, et al. · Journal of photochemistry and photobiology. B, Biology PMID:39889324 | 2025 | 1 | none stated | not extracted yet |
| Photobiomodulation for restoring salivary flow after radiotherapy in head and neck cancer: a randomised placebo-controlled trial. Lopez-Garzon 2025 · Lopez-Garzon Maria, Plata-Peregrina Maria Del Carmen, et al. · BMC oral health PMID:41013422 | 2025 | 1 | none stated | not extracted yet |
| Extraoral photobiomodulation for prevention of oral and oropharyngeal mucositis in head and neck cancer patients: interim analysis of a randomized,… Kauark-Fontes 2022 · Kauark-Fontes Elisa, Migliorati Cesar Augusto, et al. · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer PMID:34708311 | 2022 | 1 | none stated | not extracted yet |
| Impact of photobiomodulation for oral mucositis on body weight and BMI of patients with head and neck cancer. Melo 2022 · de Sousa Melo Amanda, Andrade Camila Lima, et al. · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer PMID:35169872 | 2022 | 1 | none stated | not extracted yet |
| The Effect of Photobiomodulation on Nitrite and Inflammatory Activity in Radiotherapy-Induced Oral Mucositis: A Randomized Clinical Trial. Martins 2021 · Martins Allisson F L, Morais Marília O, et al. · Lasers in surgery and medicine PMID:32997817 | 2021 | 1 | none stated | not extracted yet |
| Photobiomodulation reduces the impact of radiotherapy on oral health-related quality of life due to mucositis-related symptoms in head and neck… Martins 2021 · Martins Allisson Filipe Lopes, Morais Marília Oliveira, et al. · Lasers in medical science PMID:33113075 | 2021 | 1 | none stated | not extracted yet |
| Photobiomodulation therapy for the prevention of acute radiation dermatitis in head and neck cancer patients (DERMISHEAD trial). Robijns 2021 · Robijns Jolien, Lodewijckx Joy, et al. · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology PMID:33711412 | 2021 | 1 | none stated | not extracted yet |
| Evaluation of preventive laser photobiomodulation in patients with head and neck cancer undergoing radiochemotherapy: Laser in patients with head… Dantas 2020 · Dantas Juliana Borges de Lima, Martins Gabriela Botelho, et al. · Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry PMID:32544269 | 2020 | 1 | none stated | not extracted yet |
| Photobiomodulation with low-level laser therapy reduces oral mucositis caused by head and neck radio-chemotherapy: prospective randomized controlled… Marín-Conde 2019 · Marín-Conde F, Castellanos-Cosano L, et al. · International journal of oral and maxillofacial surgery PMID:30591391 | 2019 | 1 | none stated | not extracted yet |
| Low-level laser therapy in treatment of chemoradiotherapy-induced mucositis in head and neck cancer: results of a randomised, triple blind,… Legouté 2019 · Legouté Florence, Bensadoun René-Jean, et al. · Radiation oncology (London, England) PMID:31118057 | 2019 | 1 | none stated | not extracted yet |
| Application of red light phototherapy in the treatment of radioactive dermatitis in patients with head and neck cancer. Zhang 2018 · Zhang Xudong, Li Hongfei, et al. · World journal of surgical oncology PMID:30419911 | 2018 | 1 | none stated | not extracted yet |
| Low-Level Laser for Mitigation of Low Salivary Flow Rate in Head and Neck Cancer Patients Undergoing Radiochemotherapy: A Prospective Longitudinal… Gonnelli 2016 · Gonnelli Fernanda Aurora Stabile, Palma Luiz Felipe, et al. · Photomedicine and laser surgery PMID:27196626 | 2016 | 1 | none stated | not extracted yet |
| Low level laser therapy against radiation induced oral mucositis in elderly head and neck cancer patients-a randomized placebo controlled trial. Gautam 2015 · Gautam Ajay Prashad, Fernandes Donald J, et al. · Journal of photochemistry and photobiology. B, Biology PMID:25704314 | 2015 | 1 | none stated | not extracted yet |
| Effect of low-level laser therapy on chemoradiotherapy-induced oral mucositis and salivary inflammatory mediators in head and neck cancer patients. Oton-Leite 2015 · Oton-Leite Angélica F, Silva Geisa Badauy L, et al. · Lasers in surgery and medicine PMID:25824475 | 2015 | 1 | none stated | not extracted yet |
| Effect of low-level laser therapy on radiotherapy-induced hyposalivation and xerostomia: a pilot study. Saleh 2014 · Saleh Jamil, Figueiredo Maria Antonia Zancanaro, et al. · Photomedicine and laser surgery PMID:25302460 | 2014 | 1 | none stated | not extracted yet |
| Effect of low-level laser therapy on patient reported measures of oral mucositis and quality of life in head and neck cancer patients receiving… Gautam 2013 · Gautam Ajay Prashad, Fernandes Donald J, et al. · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer PMID:23224689 | 2013 | 1 | none stated | not extracted yet |
| Phase III trial of low-level laser therapy to prevent oral mucositis in head and neck cancer patients treated with concurrent chemoradiation. Antunes 2013 · Antunes Heliton S, Herchenhorn Daniel, et al. · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology PMID:24044799 | 2013 | 1 | none stated | not extracted yet |
| Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III… de Lima 2012 · Gouvêa de Lima Aline, Villar Rosângela Correa, et al. · International journal of radiation oncology, biology, physics PMID:21163585 | 2012 | 1 | none stated | not extracted yet |
| Effect of intraoral low-level laser therapy on quality of life of patients with head and neck cancer undergoing radiotherapy. Oton-Leite 2012 · Oton-Leite Angélica Ferreira, Corrêa de Castro Annelise Carrilho, et al. · Head & neck PMID:21472883 | 2012 | 1 | none stated | not extracted yet |
| Low level helium neon laser therapy for chemoradiotherapy induced oral mucositis in oral cancer patients - a randomized controlled trial. Gautam 2012 · Gautam Ajay Prashad, Fernandes Donald J, et al. · Oral oncology PMID:22502814 | 2012 | 1 | none stated | not extracted yet |
| Low level laser therapy for concurrent chemoradiotherapy induced oral mucositis in head and neck cancer patients - a triple blinded randomized… Gautam 2012 · Gautam Ajay Prashad, Fernandes Donald J, et al. · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology PMID:22884841 | 2012 | 1 | none stated | not extracted yet |
| Use of 660-nm diode laser in the prevention and treatment of human oral mucositis induced by radiotherapy and chemotherapy. Zanin 2010 · Zanin Taís, Zanin Fatima, et al. · Photomedicine and laser surgery PMID:19764899 | 2010 | 1 | none stated | not extracted yet |
| Effect of low level helium-neon (He-Ne) laser therapy in the prevention & treatment of radiation induced mucositis in head & neck cancer patients. Maiya 2006 · Arun Maiya G, Sagar M S, et al. · The Indian journal of medical research PMID:17159259 | 2006 | 1 | none stated | not extracted yet |
| Low-energy He/Ne laser in the prevention of radiation-induced mucositis. A multicenter phase III randomized study in patients with head and neck… Bensadoun 1999 · Bensadoun R J, Franquin J C, et al. · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer PMID:10423050 | 1999 | 1 | none stated | not extracted yet |
| Fernandes 2023 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Libik 2017 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Lopes 2006 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |