Trials
Trials and primary studies
Every primary study the non-Cochrane dental caries reviews include, resolved to one record per study so a trial included by several reviews is counted once. Most are randomized trials; aetiology and diagnostic reviews also include observational and accuracy studies.
Primary studies
5,083
2,113 PMID · 1,332 DOI · 1,638 author and year
In two or more reviews
277
overlap between reviews
Trial PICO extracted
0
extraction not run yet
Per-trial results
0
extraction not run yet
ReviewStudies included by The association of fluoride exposure with bone density and fracture risk: a dose-response meta-analysis.. Show all studies
74 studies, most shared first
| Study | Year | Reviews | Outcome links | Trial PICO |
|---|---|---|---|---|
| Association of fluoride exposure with disease burden and neurodevelopment outcomes in children in South Korea Lee et al. 2024 · Lee Won Seok, Kim Ju Hee, et al. · World Journal of Pediatrics DOI:10.1007/s12519-024-00820-3 | 2024 | 1 | none stated | not extracted yet |
| The Association between Fluoride and Bone Mineral Density in US Children and Adolescents: A Pilot Study. Kong et al. 2024 · Kong Haichen, He Zihao, et al. · Nutrients PMID:39275266 | 2024 | 1 | none stated | not extracted yet |
| Fluoride in Drinking Water, Diet, and Urine in Relation to Bone Mineral Density and Fracture Incidence in Postmenopausal Women. Helte et al. 2021 · Helte Emilie, Donat Vargas Carolina, et al. · Environmental health perspectives PMID:33822648 | 2021 | 1 | none stated | not extracted yet |
| Bone quality in fluoride-exposed populations: A novel application of the ultrasonic method. Godebo et al. 2020 · Godebo Tewodros Rango, Jeuland Marc, et al. · Bone reports PMID:31890757 | 2020 | 1 | none stated | not extracted yet |
| Community water fluoridation and health outcomes in England: a cross‐sectional study Young et al. 2015 · Young Nicholas, Newton John, et al. · Community Dentistry and Oral Epidemiology DOI:10.1111/cdoe.12180 | 2015 | 1 | none stated | not extracted yet |
| Effects of life-long fluoride intake on bone measures of adolescents: a prospective cohort study. Levy et al. 2014 · Levy S M, Warren J J, et al. · Journal of dental research PMID:24470542 | 2014 | 1 | none stated | not extracted yet |
| Estimated Drinking Water Fluoride Exposure and Risk of Hip Fracture Nasman et al. 2013 · Näsman P., Ekstrand J., et al. · Journal of Dental Research DOI:10.1177/0022034513506443 | 2013 | 1 | none stated | not extracted yet |
| Change of urinary fluoride and bone metabolism indicators in the endemic fluorosis areas of southern China after supplying low fluoride public water. Chen et al. 2013 · Chen Shaoxian, Li Boling, et al. · BMC public health PMID:23425550 | 2013 | 1 | none stated | not extracted yet |
| Elevated Serum Fluoride Concentrations in Women Are Not Related to Fractures and Bone Mineral Density Sowers et al. 2005 · Sowers MaryFran, Whitford Gary M., et al. · The Journal of Nutrition DOI:10.1093/jn/135.9.2247 | 2005 | 1 | none stated | not extracted yet |
| Effect of Long-Term Exposure to Fluoride in Drinking Water on Risks of Bone Fractures Li et al. 2001 · Li Yiming, Liang Chaoke, et al. · Journal of Bone and Mineral Research DOI:10.1359/jbmr.2001.16.5.932 | 2001 | 1 | none stated | not extracted yet |
| Fluoride in drinking water and risk of hip fracture in the UK: a case-control study Hillier et al. 2000 · Hillier Sharon, Cooper Cyrus, et al. · The Lancet DOI:10.1016/s0140-6736(99)07161-5 | 2000 | 1 | none stated | not extracted yet |
| Community water fluoridation, bone mineral density, and fractures: prospective study of effects in older women. Phipps et al. 2000 · Phipps K R, Orwoll E S, et al. · BMJ (Clinical research ed.) PMID:11021862 | 2000 | 1 | none stated | not extracted yet |
| Whole-Body Bone Mineral Measurements in 15-Year-Old Swedish Adolescents Lotborn et al. 1999 · Lötborn M., Bratteby L.-E., et al. · Osteoporosis International DOI:10.1007/s001980050122 | 1999 | 1 | none stated | not extracted yet |
| Bone-Fracture Incidence Rate in Two Italian Regions with Different Fluoride Concentration Levels in Drinking Water Fabiani et al. 1999 · Fabiani L., Leoni V., et al. · Journal of Trace Elements in Medicine and Biology DOI:10.1016/s0946-672x(99)80041-8 | 1999 | 1 | none stated | not extracted yet |
| Exposure to Natural Fluoride in Well Water and Hip Fracture: A Cohort Analysis in Finland Kurttio et al. 1999 · Kurttio P., Gustavsson N., et al. · American Journal of Epidemiology DOI:10.1093/oxfordjournals.aje.a010086 | 1999 | 1 | none stated | not extracted yet |
| 3rinking water fluoridation: Bone mineral density and hip fracture incidence Lehmann et al. 1998 · Lehmann R., Wapniarz M., et al. · Bone DOI:10.1016/s8756-3282(97)00273-1 | 1998 | 1 | none stated | not extracted yet |
| Use of Toenail Fluoride Levels as an Indicator for the Risk of Hip and Forearm Fractures in Women Feskanich et al. 1998 · Feskanich Diane, Owusu William, et al. · Epidemiology DOI:10.1097/00001648-199807000-00011 | 1998 | 1 | none stated | not extracted yet |
| The Association Between Water-borne Fluoride and Bone Mineral Density in Older Adults Phipps et al. 1998 · Phipps K.R., Orwoll E.S., et al. · Journal of Dental Research DOI:10.1177/00220345980770091001 | 1998 | 1 | none stated | not extracted yet |
| The effect of water fluoridation on the bone mineral density of young women. Arnold et al. 1997 · Arnold C M, Bailey D A, et al. · Canadian journal of public health = Revue canadienne de sante publique PMID:9458565 | 1997 | 1 | none stated | not extracted yet |
| Patterns of fracture among the United States elderly: Geographic and fluoride effects Karagas et al. 1996 · Karagas Margaret R., Baron John A., et al. · Annals of Epidemiology DOI:10.1016/1047-2797(96)00006-3 | 1996 | 1 | none stated | not extracted yet |
| Effects of fluoridated drinking water on bone mass and fractures: The study of osteoporotic fractures Cauley et al. 1995 · Cauley Jane A., Buhari Alhaji M., et al. · Journal of Bone and Mineral Research DOI:10.1002/jbmr.5650100712 | 1995 | 1 | none stated | not extracted yet |
| Fluoride in Drinking Water and the Bone Mineral Density of Women in Taiwan Lan et al. 1995 · LAN CHUNG-FU, LIN I-FENG, et al. · International Journal of Epidemiology DOI:10.1093/ije/24.6.1182 | 1995 | 1 | none stated | not extracted yet |
| The effect of fluoridated drinking water on axial bone mineral density — a population-based study Kroger et al. 1994 · Kröger Heikki, Alhava Esko, et al. · Bone and Mineral DOI:10.1016/s0169-6009(08)80184-5 | 1994 | 1 | none stated | not extracted yet |
| The fluoridation of drinking water and hip fracture hospitalization rates in two Canadian communities. Suarez-Almazor et al. 1993 · Suarez-Almazor M E, Flowerdew G, et al. · American journal of public health PMID:8484450 | 1993 | 1 | none stated | not extracted yet |
| Hip Fractures and Fluoridation in Utah's Elderly Population Danielson et al. 1992 · Danielson Christa · JAMA: The Journal of the American Medical Association DOI:10.1001/jama.1992.03490060078027 | 1992 | 1 | none stated | not extracted yet |
| The association between water fluoridation and hip fracture among white Women and Men aged 65 years and older Jacobsen et al. 1992 · Jacobsen Steven J., Goldberg Jack, et al. · Annals of Epidemiology DOI:10.1016/1047-2797(92)90006-c | 1992 | 1 | none stated | not extracted yet |
| A Prospective Study of Bone Mineral Content and Fracture in Communities with Differential Fluoride Exposure Sowers et al. 1991 · Sowers MaryFran R., Clerk Kathleen M., et al. · American Journal of Epidemiology DOI:10.1093/oxfordjournals.aje.a115940 | 1991 | 1 | none stated | not extracted yet |
| Water-borne Fluoride and Cortical Bone Mass: A Comparison of Two Communities Phipps et al. 1990 · Phipps K.R., Burt B.A. · Journal of Dental Research DOI:10.1177/00220345900690060601 | 1990 | 1 | none stated | not extracted yet |
| Water fluoride concentration and fracture of the proximal femur. Cooper et al. 1990 · Cooper C, Wickham C, et al. · Journal of epidemiology and community health PMID:2348142 | 1990 | 1 | none stated | not extracted yet |
| Hip fracture incidence not affected by fluoridation: Osteofluorosis studied in Finland Arnala et al. 1986 · Arnala Iikka, Alhava Esko M., et al. · Acta Orthopaedica Scandinavica DOI:10.3109/17453678608994408 | 1986 | 1 | none stated | not extracted yet |
| DOES FLUORIDATION OF DRINKING-WATER PREVENT BONE FRAGILITY AND OSTEOPOROSIS? Simonen et al. 1985 · Simonen Olli, Laitinen Ossi · The Lancet DOI:10.1016/s0140-6736(85)92748-5 | 1985 | 1 | none stated | not extracted yet |
| The Effect of Drinking Water Fluoridation on the Fluoride Content, Strength and Mineral Density of Human Bone Alhava et al. 1980 · Alhava E. M., Olkkonen H., et al. · Acta Orthopaedica Scandinavica DOI:10.3109/17453678008990817 | 1980 | 1 | none stated | not extracted yet |
| [Effect of alcoholic intoxication on the body's natural resistance to exposure to infectious and toxic agents]. McClure et al. 1944 · Aver'ianova L L, Fomina V G · Zhurnal mikrobiologii, epidemiologii i immunobiologii PMID:194439 | 1977 | 1 | none stated | not extracted yet |
| Interactions between spinach ferredoxin and other electron carriers. The involvement of a ferredoxin:cytochrome c complex in the ferredoxin-linked… Goggin et al. 1965 · Davis D J, San Pietro A · Archives of biochemistry and biophysics PMID:196554 | 1977 | 1 | none stated | not extracted yet |
| An inhibitor of mammalian collagenase from foetal rabbit bone in culture. Korns et al. 1969 · Sellers A, Cartwright E, et al. · Biochemical Society transactions PMID:196958 | 1977 | 1 | none stated | not extracted yet |
| [Participation of the alpha- and beta-adrenoreactive systems of the brain in the regulation of contractile thermogenesis in the cat]. Alhava et al. 1980 · Lupandin Iu V · Biulleten' eksperimental'noi biologii i meditsiny PMID:198040 | 1977 | 1 | none stated | not extracted yet |
| Experimental carcinoma of liver in macaque monkeys exposed to diethylnitrosamine and hepatitis B virus. Simonen et al. 1985 · Gyorkey F, Melnick J L, et al. · Journal of the National Cancer Institute PMID:198564 | 1977 | 1 | none stated | not extracted yet |
| [Functional anatomy of low back pain and ischialgia (author's transl)]. Arnala et al. 1986 · Struppler A · MMW, Munchener medizinische Wochenschrift PMID:198649 | 1977 | 1 | none stated | not extracted yet |
| Adenosine in rat cerebral cortex: its determination, normal values, and correlation to AMP and cyclic AMP during shortlasting ischemia. Phipps et al. 1990 · Nordström C H, Rehncrona S, et al. · Acta physiologica Scandinavica PMID:199047 | 1977 | 1 | none stated | not extracted yet |
| On the functional significance of sleep. Cooper et al. 1990 · Oniani T N · Acta neurobiologiae experimentalis PMID:199050 | 1977 | 1 | none stated | not extracted yet |
| Calorimetric investigation of NAD binding to some dehydrogenases. Sowers et al. 1991 · Subramanian S, Ross P D · Biochemical and biophysical research communications PMID:199172 | 1977 | 1 | none stated | not extracted yet |
| Hydroxylamine oxidoreductase of Nitrosomonas. Oxidation of diethyldithiocarbamate concomitant with stimulation of nitrite synthesis. Danielson et al. 1992 · Hooper A B, Terry K R, et al. · Biochimica et biophysica acta PMID:199251 | 1977 | 1 | none stated | not extracted yet |
| Infidelity of DNA synthesis by themperature-sensitive DNA polymerases from RNA tumor viruses. Jacobsen et al. 1992 · Weymouth L A, Loeb L A · Biochimica et biophysica acta PMID:199256 | 1977 | 1 | none stated | not extracted yet |
| [Biopharmaceutic aspects of the creation of new diagnostic agents for roentgenoscopy and bronchography]. Kroger et al. 1994 · Bashura G S, Obolentseva G V, et al. · Farmatsiia PMID:199468 | 1977 | 1 | none stated | not extracted yet |
| Production of hybrid cells by fusion of human malignant tumour cells and primary mouse embryo cells. Lan et al. 1995 · Watkins J F · International journal of cancer PMID:199545 | 1977 | 1 | none stated | not extracted yet |
| Isolated, ventilated, perfused newborn rabbit lung preparation and its assessment. Cauley et al. 1995 · Olson E B, Orbeck H, et al. · Journal of applied physiology: respiratory, environmental and exercise physiology PMID:199567 | 1977 | 1 | none stated | not extracted yet |
| Characterization of Gazdar murine sarcoma virus by nucleic acid hybridization and analysis of viral expression in cells. Arnold et al. 1997 · Pang R H, Phillips L A, et al. · Journal of virology PMID:199741 | 1977 | 1 | none stated | not extracted yet |
| Human serum lipoproteins activate adipocyte plasma membrane adenylate cyclase. Phipps et al. 1998 · Pairault J, Levilliers J, et al. · Nature PMID:199848 | 1977 | 1 | none stated | not extracted yet |
| The involvement of dopaminergic neurotransmission in the inhibitory effect of morphine on caudate neurone activities. Feskanich et al. 1998 · Lee C M, Wong P C, et al. · Neuropharmacology PMID:199853 | 1977 | 1 | none stated | not extracted yet |
| Malignant fibrous histiocytoma of bone. Lehmann et al. 1998 · Spainer S S · The Orthopedic clinics of North America PMID:199869 | 1977 | 1 | none stated | not extracted yet |