evidencegaps
Primary study · included by 2 reviews

The effect of titanium-platelet rich fibrin on periodontal intrabony defects: A randomized controlled split-mouth clinical study.

Ozkal Eminoglu 2024 · Ozkal Eminoglu Didem, Arabaci Taner, Oztas Sahiner Gurbet Alev · PloS one · 2024

Included by

Clinical efficacy of different biomaterials for the regenerative treatment of periodontal intrabony defects: a systematic review and Bayesian network meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Ozkal Eminoglu 2024 · Table 1

The review does not say which of its outcomes this study informs.

Adjunctive Autologous Platelet Concentrates for Periodontal Regeneration in Intrabony Defects: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Non-Cochrane · intervention · 2026 · cited as Ozkal Eminoglu 2024 · Table 2; Figure 2; reference list
Outcome this study informsPooled effectEvidenceCertainty
Clinical attachment level or relative attachment level gain (mm)
Regenerative periodontal therapy with autologous platelet-concentrate adjunct (PRF, CGF, i-PRF, A-PRF, T-PRF) vs Regenerative periodontal therapy without platelet concentrate (graft only, OFD or other) · Follow-up 6 to 12 months (varied across studies)
MD 0.64 [0.38, 0.90]10 studies · 259 participantsGRADE not reported
Clinical attachment level or relative attachment level gain (mm)
Regenerative periodontal therapy with autologous platelet-concentrate adjunct (PRF, CGF, i-PRF, A-PRF, T-PRF) vs Regenerative periodontal therapy without platelet concentrate (graft only, OFD or other) · Follow-up 6 to 12 months (varied across studies)
MD 0.35 [0.08, 0.61]8 studies · 200 participantsGRADE not reported

2 including reviews in total.