Primary study · included by 1 review

Dual Mg-Reinforced PCL Membrane with a Janus Structure for Vascularized Bone Regeneration and Bacterial Elimination.

Wang 2024 · Wang Xianli, Shen Peiqi, Gu Nannan, et al. · ACS biomaterials science & engineering · 2024

Included by

Polycaprolactone Scaffolds for BONE Regeneration in Animal Models of Cranial Defects: A Systematic Review and Meta-Analysis
Non-Cochrane · intervention · 2026 · cited as Wang 2024 · Table 2; reference 12
Outcome this study informsPooled effectEvidenceCertainty
Bone regeneration (BV/TV, %) at one month (early stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1 month (early; includes follow-up up to 1 month)
QM = 9.509, df = 3, p = 0.023, R2 = 28.8%20 studiesGRADE not reported
Bone regeneration (BV/TV, %) at one month (early stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1 month (early; includes follow-up up to 1 month)
Meta-regression beta (difference in MD, %) 0.853 [-4.49, 6.195]20 studiesGRADE not reported
Bone regeneration (BV/TV, %) at one month (early stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1 month (early; includes follow-up up to 1 month)
MD 1.68 [0.34, 3.03]18 studies · 194 participantsGRADE not reported
Bone regeneration (BV/TV, %) at one month (early stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1 month (early; includes follow-up up to 1 month)
Meta-regression beta (difference in MD, %) -4.258 [-8.216, -0.3]20 studiesGRADE not reported
Bone regeneration (BV/TV, %) at one month (early stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1 month (early; includes follow-up up to 1 month)
QM = 0.703, df = 1, p = 0.402, R2 = 0%20 studiesGRADE not reported
Bone regeneration (BV/TV, %) at one month (early stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1 month (early; includes follow-up up to 1 month)
Meta-regression beta (difference in MD, %) -6.987 [-12.867, -1.108]20 studiesGRADE not reported
Bone regeneration (BV/TV, %) at one month (early stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1 month (early; includes follow-up up to 1 month)
QM = 0.334, df = 1, p = 0.563, R2 = 0%20 studiesGRADE not reported

1 including review in total.