evidencegaps
Primary study · included by 1 review

Injectable platelet-rich fibrin with demineralized freeze-dried bone allograft compared to demineralized freeze-dried bone allograft in intrabony defects of patients with stage-III periodontitis: a randomized controlled clinical trial.

Alshoiby 2023 · Alshoiby Mashaal Mohammed, Fawzy El-Sayed Karim Mohamed, Elbattawy Weam, et al. · Clinical oral investigations · 2023

Included by

Adjunctive Autologous Platelet Concentrates for Periodontal Regeneration in Intrabony Defects: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Non-Cochrane · intervention · 2026 · cited as Alshoiby 2023 · Table 2; Figure 2; reference list
Outcome this study informsPooled effectEvidenceCertainty
Clinical attachment level or relative attachment level gain (mm)
Regenerative periodontal therapy with autologous platelet-concentrate adjunct (PRF, CGF, i-PRF, A-PRF, T-PRF) vs Regenerative periodontal therapy without platelet concentrate (graft only, OFD or other) · Follow-up 6 to 12 months (varied across studies)
MD 0.64 [0.38, 0.90]10 studies · 259 participantsGRADE not reported
Clinical attachment level or relative attachment level gain (mm)
Regenerative periodontal therapy with autologous platelet-concentrate adjunct (PRF, CGF, i-PRF, A-PRF, T-PRF) vs Regenerative periodontal therapy without platelet concentrate (graft only, OFD or other) · Follow-up 6 to 12 months (varied across studies)
MD 0.35 [0.08, 0.61]8 studies · 200 participantsGRADE not reported

1 including review in total.