Primary study · included by 1 review
Enrichment of Prevotella intermedia in human colorectal cancer and its additive effects with Fusobacterium nucleatum on the malignant transformation of colorectal adenomas.
Lo 2022 · Lo Chia-Hui, Wu Deng-Chyang, Jao Shu-Wen, et al. · Journal of biomedical science · 2022
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Pooled prevalence of F. nucleatum in colorectal tumor tissue Fusobacterium nucleatum detection in tumor tissue | Proportion 0.45 [0.34, 0.57] | 6 studies · 818 participants | GRADE not reported |
Development of colorectal cancer (pooled hazard ratio) Presence or detection of Fusobacterium nucleatum vs No detection of F. nucleatum | HR 3.70 [1.21, 11.32] | 5 studies | GRADE not reported |
Development of colorectal cancer (pooled risk ratio, tumor vs control or normal tissue or stool) Presence or detection of Fusobacterium nucleatum vs No detection of F. nucleatum | RR 3.20 [1.76, 5.82] | 6 studies · 1044 participants | GRADE not reported |
1 including review in total.