Primary study · included by 2 reviews

Clinicoradiographic evaluation of advanced-platelet rich fibrin block (A PRF + i PRF + nanohydroxyapatite) compared to nanohydroxyapatite alone in the management of periodontal intrabony defects.

Mallappa 2022 · Mallappa Jayasheela, Vasanth Deepa, Gowda Triveni Mavinakote, et al. · Journal of Indian Society of Periodontology · 2022

Included by

Outcome this study informsPooled effectEvidenceCertainty
Radiographic bone fill or defect-depth reduction (mm)
Regenerative periodontal therapy with autologous platelet-concentrate adjunct (PRF, CGF, i-PRF, A-PRF, T-PRF) vs Regenerative periodontal therapy without platelet concentrate (graft only, OFD or other) · Follow-up 6 to 12 months (varied across studies)
MD 0.57 [-0.06, 1.20]5 studies · 123 participantsGRADE not reported
Clinical attachment level or relative attachment level gain (mm)
Regenerative periodontal therapy with autologous platelet-concentrate adjunct (PRF, CGF, i-PRF, A-PRF, T-PRF) vs Regenerative periodontal therapy without platelet concentrate (graft only, OFD or other) · Follow-up 6 to 12 months (varied across studies)
MD 0.64 [0.38, 0.90]10 studies · 259 participantsGRADE not reported
Clinical attachment level or relative attachment level gain (mm)
Regenerative periodontal therapy with autologous platelet-concentrate adjunct (PRF, CGF, i-PRF, A-PRF, T-PRF) vs Regenerative periodontal therapy without platelet concentrate (graft only, OFD or other) · Follow-up 6 to 12 months (varied across studies)
MD 0.35 [0.08, 0.61]8 studies · 200 participantsGRADE not reported

The review does not say which of its outcomes this study informs.

2 including reviews in total.