evidencegaps
Primary study · included by 2 reviews

The Effect of Treatment With Clear Aligners Versus Fixed Appliances on Oral Health-Related Quality of Life in Patients With Severe Crowding: A One-Year Follow-Up Randomized Controlled Clinical Trial.

Jaber 2022 · Jaber Samer T, Hajeer Mohammad Y, Burhan Ahmad S, et al. · Cureus · 2022

Included by

Oral Health-Related Quality of Life (OHRQoL), Pain and Side Effects in Adults Undergoing Different Orthodontic Treatment Modalities: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2025 · cited as Jaber et al. 2022 · Table 1; Figures 3-8
Outcome this study informsPooled effectEvidenceCertainty
Pain (VAS)
Clear aligners vs Within-group change, 7 days versus 24 hours after appliance fit · 24 hours to 7 days
SMD -10.02 [-11.13, -8.91]2 studies · 88 participantsGRADE not reported
Evaluation of Pain and Oral Health-Related Quality of Life Associated With Fixed Orthodontic Treatment in Adults: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Jaber 2022 · Table 2; reference list
Outcome this study informsPooled effectEvidenceCertainty
Oral health-related quality of life (OHIP-14; higher score = worse)
Conventional fixed orthodontic appliance treatment vs OHRQoL at week 1 versus month 1 after appliance placement · Week 1 versus month 1
MD 9.5 [7.5, 11.5]2 studies · 40 participantsLow

2 including reviews in total.