evidencegaps
Primary study · included by 2 reviews

The effect of micro-osteoperforations on orthodontic space closure investigated over 12 weeks: a split-mouth, randomized controlled clinical trial.

Li et al · Li Jiaojiao, Papadopoulou Alexandra K, Gandedkar Narayan, et al. · European journal of orthodontics · 2022

Included by

Effect of Micro-Osteoperforations on Orthodontic Tooth Movement: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Li 2022 · Reference list (refs 15 to 17, 23 to 58); Appendix Figure 2 forest plot

The review does not say which of its outcomes this study informs.

Micro-osteoperforation for accelerating orthodontic tooth movement: a meta-analysis of short-term efficacy, safety, and optimal application parameters.
Non-Cochrane · intervention · 2026 · cited as Li 2022 · Fig 4 and Fig 5 forest plots; Table 1; ref 16
Outcome this study informsPooled effectEvidenceCertainty
Total orthodontic tooth movement distance (mm)
Micro-osteoperforation (MOPs) adjunctive to fixed orthodontic treatment vs Conventional orthodontic treatment without MOPs · Follow-up 1 to 7.6 months across included trials
MD 0.67 [0.45, 0.88]14 studies · 484 participantsModerate

2 including reviews in total.