Primary study · included by 2 reviews

Effect of final irrigation with sodium hypochlorite at different temperatures on postoperative pain level and antibacterial activity: a randomized controlled clinical study.

Karataş 2021 · KarataŞ Ertuğrul, Ayaz Nilay, UlukÖylÜ Esra, et al. · Journal of applied oral science : revista FOB · 2021

Included by

Non-Cochrane · intervention · 2026 · cited as Karatas 2021 · Table 2; References 7, 13-22

The review does not say which of its outcomes this study informs.

Non-Cochrane · intervention · 2026 · cited as Karatas 2021 · Table 1; Results text and Figs. 2-6

Outcome this study informs	Pooled effect	Evidence	Certainty
Postoperative pain intensity (VAS/NRS) Intracanal cryotherapy (cold irrigant, 1.5 to 4 C) vs Irrigation at room temperature · 72 h	SMD -0.38 [-0.83, 0.07]	2 studies	GRADE not reported
Postoperative pain intensity (VAS/NRS) Intracanal cryotherapy (cold irrigant, 1.5 to 4 C) vs Irrigation at room temperature · 72 h	SMD -0.70 [-1.34, -0.07]	3 studies · 122 participants	High
Postoperative pain intensity (VAS/NRS) Intracanal cryotherapy (cold irrigant, 1.5 to 4 C) vs Irrigation at room temperature · 48 h	SMD -0.53 [-0.72, -0.34]	6 studies · 440 participants	High
Postoperative pain intensity (VAS/NRS) Intracanal cryotherapy (cold irrigant, 1.5 to 4 C) vs Irrigation at room temperature · 24 h	SMD -0.58 [-0.89, -0.27]	11 studies · 700 participants	High

2 including reviews in total.