evidencegaps
Primary study · included by 1 review

Postoperative Pain after Endodontic Treatment under Irrigation with 8.25% Sodium Hypochlorite and Other Solutions: A Randomized Clinical Trial.

Demenech 2021 · Demenech Luciana Stadler, de Freitas Jéssica Vavassori, Tomazinho Flávia Sens Fagundes, et al. · Journal of endodontics · 2021

Included by

Effect of Different Sodium Hypochlorite Concentrations on Post Endodontic Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Non-Cochrane · intervention · 2026 · cited as Demenech 2021 · Table 2; Study Selection; References; Figures 4-6
Outcome this study informsPooled effectEvidenceCertainty
Post-operative pain occurrence (any pain vs none) at 24 h
Low concentration sodium hypochlorite irrigation (0.5% to 2.5%) vs High concentration sodium hypochlorite irrigation (5% to 8.25%) · 24 h after root canal treatment
OR 0.69 [0.23, 2.09]4 studies · 480 participantsModerate
Post-operative pain occurrence (any pain vs none) at 72 h
Low concentration sodium hypochlorite irrigation (0.5% to 2.5%) vs High concentration sodium hypochlorite irrigation (5% to 8.25%) · 72 h after root canal treatment
OR 0.73 [0.12, 4.34]4 studies · 480 participantsModerate
Post-operative pain occurrence (any pain vs none) at 48 h
Low concentration sodium hypochlorite irrigation (0.5% to 2.5%) vs High concentration sodium hypochlorite irrigation (5% to 8.25%) · 48 h after root canal treatment
OR 0.56 [0.11, 2.76]4 studies · 480 participantsModerate

1 including review in total.