evidencegaps
Primary study · included by 1 review

Progression of Physical Frailty and the Risk of All-Cause Mortality: Is There a Point of No Return?

Xue 2021 · Xue Qian-Li, Bandeen-Roche Karen, Tian Jing, et al. · Journal of the American Geriatrics Society · 2021

Included by

Association of frailty and mortality risk in community-dwelling older adults: a systematic review and meta-analysis of 59 international prospective cohort studies.
Non-Cochrane · prognostic · 2026 · cited as Xue 2021 · Table 1; reference [53]; Fig. 2
Outcome this study informsPooled effectEvidenceCertainty
All-cause mortality
Non-robust (frail, prefrail or equivalent) on any frailty instrument vs Robust (no signs of frailty) · Follow-up 1 to 15 years
HR 1.83 [1.70, 1.97]56 studiesGRADE not reported
All-cause mortality
Non-robust (frail, prefrail or equivalent) on any frailty instrument vs Robust (no signs of frailty) · Follow-up 1 to 15 years
HR 1.11 [1.11, 1.29]NRGRADE not reported
All-cause mortality
Non-robust (frail, prefrail or equivalent) on any frailty instrument vs Robust (no signs of frailty) · Follow-up 1 to 15 years
HR 1.46 [1.27, 1.68]NRGRADE not reported

1 including review in total.