Primary study · included by 1 review

Familial associations for rheumatoid autoimmune diseases.

Thomsen 2020a · Thomsen Hauke, Li Xinjun, Sundquist Kristina, et al. · Rheumatology advances in practice · 2020

Included by

Familial and genetic overlap between Sjögren's disease and other autoimmune diseases.

Non-Cochrane · aetiology · 2026 · cited as Thomsen 2020a · Table 1; reference 29; Figures 2-4

Outcome this study informs	Pooled effect	Evidence	Certainty
Familial risk of any other autoimmune disease in first-degree relatives Proband SjD (exposure) vs Probands or controls without the disease of interest	RR 4.25 [1.85, 9.79]	4 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband SjD (exposure) vs Probands or controls without the disease of interest	RR 9.62 [8.47, 10.92]	3 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband IIM (exposure) vs Probands or controls without the disease of interest	RR 0.47 [0.17, 1.28]	3 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband SjD (exposure) vs Probands or controls without the disease of interest	RR 10.54 [7.85, 14.16]	3 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband RA (exposure) vs Probands or controls without the disease of interest	RR 1.92 [1.71, 2.14]	2 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband SLE (exposure) vs Probands or controls without the disease of interest	RR 4.49 [2.87, 7.03]	3 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband SSc (exposure) vs Probands or controls without the disease of interest	RR 2.65 [1.66, 4.21]	2 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband RA (exposure) vs Probands or controls without the disease of interest	RR 2.21 [1.28, 3.82]	2 studies	GRADE not reported
Familial risk of any other autoimmune disease in first-degree relatives Proband SjD (exposure) vs Probands or controls without the disease of interest	RR 7.38 [6.38, 8.54]	4 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband SSc (exposure) vs Probands or controls without the disease of interest	RR 2.65 [1.66, 4.21]	2 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband SLE (exposure) vs Probands or controls without the disease of interest	RR 4.94 [4.26, 5.72]	3 studies	GRADE not reported
Familial risk of SjD in first-degree relatives Proband IIM (exposure) vs Probands or controls without the disease of interest	RR 0.47 [0.17, 1.28]	3 studies	GRADE not reported

1 including review in total.