Primary study · included by 1 review

Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study.

Lo 2021 · Lo Chun-Han, Kwon Sohee, Wang Liang, et al. · Gut · 2021

Included by

Tooth loss and infrequent brushing significantly elevate gastric cancer risk: an updated systematic review and meta-analysis with heterogeneity exploration.

Non-Cochrane · aetiology · 2026 · cited as Lo 2021 · Supplementary Table S7; reference list

Outcome this study informs	Pooled effect	Evidence	Certainty
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.20 [1.13, 1.27]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.23 [1.13, 1.34]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.07, 1.31]	7 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.34 [1.12, 1.61]	8 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.12, 1.26]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.22 [1.15, 1.30]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.12, 1.27]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.18 [1.11, 1.26]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.43 [1.12, 1.82]	5 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.20 [1.13, 1.27]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.20 [1.13, 1.27]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.12, 1.26]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.20 [1.13, 1.28]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.68 [1.22, 2.32]	3 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.21 [1.13, 1.28]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.12, 1.26]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.23 [1.11, 1.36]	7 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.12, 1.27]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.21 [0.88, 1.66]	4 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.07, 1.31]	5 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.25 [1.12, 1.39]	10 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.30 [0.83, 2.04]	3 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.12, 1.26]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.20 [1.13, 1.27]	10 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.25 [1.12, 1.40]	6 studies	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.20 [1.13, 1.27]	NR	GRADE not reported
Gastric cancer incidence Tooth loss (highest category of teeth lost) vs Least tooth loss (lowest category)	OR 1.19 [1.12, 1.26]	NR	GRADE not reported

1 including review in total.