Primary study · included by 1 review

Computer-Aided Design and Manufacturing Cutting and Drilling Guides with Prebent Titanium Plates Improve Surgical Accuracy of Skeletal Class III Malocclusion.

Li 2020 · Li Kehan, Li Jiayang, Du Wen, et al. · Plastic and reconstructive surgery · 2020

Included by

Patient-specific guides and osteosynthesis versus CAD/CAM occlusal splints in orthognathic surgery: a systematic review and meta-analysis of accuracy, operative time, and complications.

Non-Cochrane · intervention · 2026 · cited as Li 2020 · Table 1; Fig. 2-7; reference list [35]

Outcome this study informs	Pooled effect	Evidence	Certainty
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.54 [-0.89, -0.18]	7 studies	GRADE not reported
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.40 [-0.69, -0.11]	15 studies	GRADE not reported
Combined three-dimensional linear deviation (mm), supportive summary Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.51 [-0.70, -0.33]	14 studies	GRADE not reported
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.50 [-1.77, 0.78]	4 studies	GRADE not reported
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.52 [-0.77, -0.28]	15 studies	Low
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.27 [-1.66, 1.13]	4 studies	GRADE not reported
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.54 [-1.10, 0.01]	4 studies	GRADE not reported
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.54 [-0.86, -0.22]	7 studies	GRADE not reported
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.48 [-0.78, -0.17]	15 studies	Low
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.35 [-0.93, 0.24]	8 studies	GRADE not reported
Overall postoperative complications Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Postoperative (follow-up varied)	RR 1.01 [0.64, 1.60]	9 studies · 538 participants	Low
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.54 [-0.96, -0.13]	8 studies	GRADE not reported
Combined three-dimensional linear deviation (mm), supportive summary Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.46 [-0.66, -0.25]	9 studies	GRADE not reported
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.19 [-0.40, 0.02]	4 studies	GRADE not reported
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.91 [-1.39, -0.42]	4 studies	GRADE not reported
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.36 [-2.03, 1.31]	4 studies	GRADE not reported
Operative time (minutes), total bimaxillary operation time Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Intraoperative	MD -10.77 [-47.99, 26.44]	4 studies	Very low
Combined three-dimensional linear deviation (mm), supportive summary Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.56 [-0.92, -0.19]	9 studies	GRADE not reported
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.34 [-0.89, 0.22]	7 studies	GRADE not reported
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.33 [-0.67, 0.02]	11 studies	GRADE not reported
Superoinferior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.28 [-0.62, 0.06]	15 studies	GRADE not reported
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.39 [-0.70, -0.08]	11 studies	GRADE not reported
Anteroposterior translational deviation (mm) Patient-specific implant (PSI) workflows (cutting/drilling guides and/or customized osteosynthesis plates) vs CAD/CAM occlusal splint or wafer workflows · Within 3 days to 1 month postoperative	MD -0.19 [-0.64, 0.25]	7 studies	GRADE not reported

1 including review in total.