Primary study · included by 1 review

Intra-articular injection of a mixture of hyaluronic acid and corticosteroid versus arthrocentesis in TMJ internal derangement.

Marzook 2020 · Marzook H A M, Abdel Razek A A, Yousef E A, et al. · Journal of stomatology, oral and maxillofacial surgery · 2020

Included by

Outcome this study informsPooled effectEvidenceCertainty
Pain intensity (VAS)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -1.609 [-5.033, 1.816]NRGRADE not reported
Right lateral movement
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD -1.54 [-3.64, 0.55]3 studies · 96 participantsGRADE not reported
Maximum incisal opening (MIO)
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
SMD -2.93 [-4.54, -1.32]11 studies · 325 participantsVery low
Overall mandibular movement
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD -0.40 [-0.93, 0.14]22 studies · 796 participantsVery low
Maximum incisal opening (MIO)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -1.640 [-24.881, 21.602]NRGRADE not reported
Pain intensity (VAS)
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD -0.25 [-1.09, 0.59]26 studies · 947 participantsVery low
Left lateral movement
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD -0.42 [-3.10, 2.26]3 studies · 96 participantsGRADE not reported
Maximum incisal opening (MIO)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) 0.302 [-0.231, 0.836]NRGRADE not reported
Pain intensity (VAS)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -0.028 [-0.125, 0.069]NRGRADE not reported

1 including review in total.