Primary study · included by 1 review

Oral probiotics reduce halitosis in patients wearing orthodontic braces: a randomized, triple-blind, placebo-controlled trial.

Benic et al. 2019 · Benic Gareth Z, Farella Mauro, Morgan Xochitl C, et al. · Journal of breath research · 2019

PubMed 31022704doi:10.1088/1752-7163/ab1c81Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Gene sequencing applications to combat oral-cavity related disorders: a systematic review with meta-analysis.
Non-Cochrane · prognostic · 2024 · cited as Benic et al. 2019 · Table 1 [39]; Figs. 3 and 4 (meta-analysis); ref 39 (J Breath Res 2019)
Outcome this study informsPooled effectEvidenceCertainty
Noticeable impact of gene sequencing on diagnosing/managing oral conditions
Gene sequencing (GS) applied to diagnose/manage oral conditions (predominantly 16S rRNA next-generation sequencing of the oral microbiome; also genome-wide/whole-genome sequencing) vs Negligible ('abysmal') effect of gene sequencing; no separate comparator arm (within-sample event contrast in the forest plots)
RR 0.50 [0.46, 0.54]8 studies · 2211 participantsUngraded
Noticeable impact of gene sequencing on diagnosing/managing oral conditions
Gene sequencing (GS) applied to diagnose/manage oral conditions (predominantly 16S rRNA next-generation sequencing of the oral microbiome; also genome-wide/whole-genome sequencing) vs Negligible ('abysmal') effect of gene sequencing; no separate comparator arm (within-sample event contrast in the forest plots)
OR 0.30 [0.26, 0.33]8 studies · 2211 participantsUngraded
Reduction in occurrence of oral conditions
Gene sequencing (GS) applied to diagnose/manage oral conditions (predominantly 16S rRNA next-generation sequencing of the oral microbiome; also genome-wide/whole-genome sequencing) vs Negligible ('abysmal') effect of gene sequencing; no separate comparator arm (within-sample event contrast in the forest plots)
RD -0.29 [-0.32, -0.26]8 studies · 2211 participantsUngraded

1 including review in total.